|Place of Origin:||China|
|Certification:||ISO 9001, USP, GMP|
|Minimum Order Quantity:||10g|
|Packaging Details:||Well disguised package ;Foil bag|
|Delivery Time:||3-5 work days|
|Payment Terms:||T/T, Western Union, MoneyGram,Bitcoin|
|Supply Ability:||Mass in Stock|
Antipyretic analgesics for the treatment of fever, headache, neuralgia, etc.Antipyretic analgesic drug substance
Product Name: Phenacetin
Appearance: white crystal
Number of meshes: 40
Packing: 25KG/full cardboard drum
Ingredients: 4-ethoxyacetanilide Customs Code: 2924291000 Tax Refund Rate 9%
Physicochemical properties: White glossy scaly crystals or white crystalline powder. Melting point 137-138 ° C, refractive index 1.571. Hard to dissolve in water, slightly soluble in ether, slightly soluble in boiling water, soluble in ethanol and chloroform. When it is dissolved in concentrated sulfuric acid, the color is not obvious, and it is orange-yellow after dropping nitric acid into the solution. Odorless, slightly bitter taste.
Category: Pharmaceutical Raw Materials
Field: Antipyretic Analgesia
Deferred products: Compound preparations
Use: For the treatment of fever, headache, neuralgia, etc.
Antipyretic and analgesic effects of phenacetin are similar to those of “acetylsalicylic acid” and are mainly used as antipyretic and analgesic drugs. They have a slow and long-lasting effect. They have good curative effects on headache, neuralgia, joint pain and fever. , but the anti-rheumatic and anti-inflammatory effects are weak. Excessive doses can cause methemoglobinemia, resulting in hypoxia, long-term medication can damage the kidneys, and even cause necrosis, should be used with caution. Because of its toxic side effects and rapid development of other similar drugs, the drug has stopped using it alone, but it is used as a combination of drug substances and other drugs. Aspirin and caffeine are often combined to form aspirin. Its composition is 0.162 g of phenacetin, 0.227 g of aspirin, and 0.035 g of caffeine. It is less toxic and is used to treat colds and colds. If a small amount of chlorpheniramine is added to the above drugs, it can also be used to make chlorpheniramine-sensitive cold films, which can be used to treat colds, headaches, neuralgia, and rheumatic pain.
Phenacetin itself does not have antipyretic and analgesic effects. In the body, paracetamol, which is acetaminophen, is metabolized and metabolized. It also decomposes p-aminophenyl ether, which has not only no antipyretic and analgesic effects, but is also a major factor in the toxic side effects of phenacetin.
China began producing phenacetin in 1954. It was obtained by the etherification reaction of nitrochlorobenzene with ethanol to obtain p-nitrophenyl ether, which was then reduced to p-aminophenyl ether and then acetylated with acetic acid to obtain it.
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