|Place of Origin:||China|
|Certification:||ISO 9001, USP, GMP|
|Minimum Order Quantity:||10g|
|Packaging Details:||Well disguised package ;Foil bag|
|Delivery Time:||3-5 work days|
|Payment Terms:||T/T, Western Union, MoneyGram, Bitcoin|
|Supply Ability:||Mass in Stock|
|Product Name:||Tetracaine Hydrochloride||CAS:||136-47-0|
|Purity:||99%||Appearance:||White Crystal Powder|
99% white Raw Local Anesthesia Agents powder Tetracaine HCL CAS136-47-0
|Alias:||Tetracaine hydrochloride ,2-Dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride;
4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride
|Appearance:||White Crystal Powder|
|Usage:||Local anesthetic;Mainly used in mucosa anesthetic.The function is stronger than
Procaine and Lidocaine. Tetracaine HCl is a potent local anaesthetic and a channel function allosteric inhibitor.
|Storage:||Closed, confined and shading preservation|
|Shipment Way:||EMS, HK Post, DHL, TNT, UPS, FedEx, Aramex
Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Tetracaine Hcl For topical ophthalmic use only. Not for parenteral use. Not for injection. Do not use solution if it contains crystals or if it is cloudy or discolored. Prolonged use results in diminished duration of anesthesia and retarded healing. This may cause the drug to be used more frequently, creating a “vicious circle”. Subsequent corneal infection and/or corneal opacification with accompanying permanent visual loss or corneal perforation may occur. Prolonged use may also produce severe keratitis.
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
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