Place of Origin: | China |
Brand Name: | RAWSGEAR |
Certification: | ISO 9001, USP,GMP |
Model Number: | 73-78-9 |
Minimum Order Quantity: | 10g |
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Price: | negotiable |
Packaging Details: | Disguised package ; Foil bag |
Delivery Time: | 3-7 work days |
Payment Terms: | Western Union, MoneyGram, T/T, bitcoin |
Supply Ability: | Mass in stock |
Product Name: | Lidocaine HCL | Appearance: | White Powder |
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Grade: | Pharmacetical Grade | MF: | C14H23ClN2O |
MW: | 270.8 | Usage: | Analgesic |
Shiping: | EMS,HKEMS,FEDEX,DHL,TNT,Aramex,etc | Package: | Foil Bag; Well Disguised Package |
Shipping Policy: | 100% Free Resend Shipping | ||
High Light: | topical anesthetic drugs,pain killer drugs |
Pharmaceutical Raw Materials White Powder Lidocaine HCL CAS 73-78-9 Pain Killer
Quick detail:
Product name: Lidocaine hydrochloride
Synonyms: LIDOCAINE HCl, Lidocaine HCl, Lidesthesin, Xylotox, Lidocaine HCl, Lidocaine HCl, Lidocaine hydrochloride, Lidocaine hydrochloride USP, Lidocaine hydrochloride supplier
CAS:73-78-9
MF:C14H23ClN2O
MW:270.8
EINECS:200-803-8
Appearance:White to Off-White Solid
Usage:Anesthetic (local); antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic.
Product Name |
Lidocaine Hydrochloride |
Synonyms |
Lidocaine HCL; Lidocaine HCI; 2-DIETHYLAMINO-N-(2'6'-DIMETHYLPHENYL)ACETAMIDE HCL;2-DIETHYLAMINO-N-[2,6-DIMETHYLPHENYL]ACETAMIDE HCL;ALPHA-(DIETHYLAMINO)-2',6'-ACETOXYLIDIDE HYDROCHLORIDE;A-(DIETHYLAMINO)-2 6-DIMETHYLACETANILIDE HYDROCHLORIDE;LIGNOCAINE HYDROCHLORIDE;LIDOCAINE HYDROCHLORIDE;LIDOCAINE HCL;2-(diethylamino)-n-(2,6-dimethylphenyl)-acetamidmonohydrochloride |
CAS |
73-78-9 |
MF |
C14H23ClN2O |
MW |
270.8 |
EINECS |
200-803-8 |
Appearance |
White crystalline powder |
Assay |
99.52% |
Standard |
USP |
Mini Order |
100g |
Usage |
Local anesthesic;Na+ channel blocker; Anesthetic (local); antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic. |
Description:
Local Anesthetic Drugs Lidocaine, also known as xylocaine and lignocaine , is a medication used to numb tissue in a specific area and to treat ventricular tachycardia . It can also be used for nerve blocks . Lidocaine mixed with a small amount of epinephrine is available to allow larger doses to be used as numbing and to make it last longer . When used as an injectable it typically begins working within four minutes and lasts for half an hour to three hours . Lidocaine may also be applied directly to the skin for numbing.
Common side effects with intravenous use include sleepiness, muscle twitching , confusion , changes in vision , numbness , tingling, and vomiting . It can cause low blood pressure and an irregular heart rate.There are concerns that injecting it into a joint can cause problems with the cartilage . It appears to be generally safe for use in pregnancy . A lower dose may be required in those with liver problems . It is generally safe to use in those allergic to tetracaine or benzocaine . Lidocaine is an antiarrhythmic medication of the class Ib type . Lidocaine works by blocking sodium channels and thus decreasing the rate of contractions of the heart . When used locally as a numbing agent, local neurons cannot signal the brain.
Lidocaine hydrochloride is a white powder without smell and with a bitter taste that is used both in human and veterinary medicine. The drug is also known as lignocaine hydrochloride, and is used as a local anesthetic and to regulate certain medical problems related to heart rhythm. Injections of it are used to provide local anesthesia during various minor surgical procedures. It is also available in various topical preparations, such as gels, sprays, creams, and ointments that are usually applied to the skin or the mucous membranes. This drug was first manufactured in Sweden in 1943 and was then named xylocaine.
The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine, on the other hand, has the advantage of a rapid onset of action.
Epinephrine(aka adrenaline)vasoconstricts arteries reducing bleeding and also delays the resorption of lidocaine,almost doubling the duration of anaesthesia.For surface anesthesia several formulations are available that can be used e.g.for endoscopies,before intubations etc. Buffering the pH of lidocaine makes local freezing less painful.Lidocaine drops can be used on the eyes for short ophthalmic procedures.
Topical lidocaine has been shown in some patients to relieve the pain of postherpetic neuralgia complication of shingles),though there is not enough study evidence to recommend it as a first-line treatment.IV lidocaine also has uses as a temporary fix for tinnitus.Although no completely curing the disorder,it has been shown to reduce the effects by around two thirds.
Lidocaine hydrochloride injection administered intravenously or intramuscularly,is specifically indicated in the acute management of ventricular arrhythmias such as those occurring in relation to acute myocardial infarction,or during cardiac manipulation,such as cardiac surgery.
Applications:
The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy . Therefore, lidocaine is suitable for infiltration , block , and surface anesthesia . Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias ; lidocaine , though , has the advantage of a rapid onset of action . Epinephrine vasoconstricts arteries , reducing bleeding and also delays the resorption of lidocaine , almost doubling the duration of anaesthesia . For surface anesthesia, several available formulations can be used for endoscopies , before intubations , etc . Buffering the pH of lidocaine makes local numbing less painful . Lidocaine drops can be used on the eyes for short ophthalmic procedures . There is tentative evidence for topical lidocaine for neuropathic pain.
Lidocaine, as a local anesthetic, is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias. lidocaine, on the other hand, has the advantage of a rapid onset of action.
It can stop Epinephrine vasoconstricts arteries form bleeding, and it can also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. Lidocaine hydrochloride injection administered intravenously or intramuscularly, is specifically indicated in the acute management of ventricular arrhythmias such as those occurring in relation to acute myocardial infarction, or during cardiac manipulation, such as cardiac surgery.
Lidocaine is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide.
The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of Lidocaine. Approximately 90% of Lidocaine administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2, 6-dimethylaniline. so-hansi-font-family:Calibri;mso-bidi-font-family.
Main functions:
Local anesthetic;
Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine;
For block anesthesia and epidural anesthesia;
As painkillers of injection in the medicament;
Also used in suppository and ointment preparation, etc;
Also used for ventricular arrhythmias caused by myocardial infarction, digitalism, glucantime poisoning, surgery and so on. Such as ventricular tachycardia, frequent ventricular premature beat, ventricular fibrillation.
Lidocaine HCI Test Report(COA):
Competitive Advantage:
1. Our company is a professional production leading factory in China in pharmaceutical area of many years.
Delivery areas of our products: US, UK, Canada, Australia, Brazil, Russia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on.
Payment method: T/T, Western union, Moneygram, bitcoin etc.
2. Discreet package. The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration.
3. Top quality. High quality guarenteed, once any problem is found, the package would be reshipped for you.
4. Security Shipping: Shipping by express (FedEx, UPS, DHL, EMS), by air. The most professional forwarder would be recommanded for you.
5. We have stock, so we can delivery quickly at the very day when receive the payment.
6. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.
7. A discount would be given when you make a large order.
Tips:
HOW TO MAKE AN ORDER?
1. Tell us what you need ( use for what/product name & quantity ), you will get an advice and a quotation.
2. Full payment would be done once we come to an agreement on all details .
3. Your goods will be sent out within 24 hours after payment , tracking number available.
4. The goods will reach you in 3~7 days.
WHY CHOOSE US?
1. High quality: Our factories are professional in raw powder production with experience over 10 years. Having good reputation all over the world, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
2. Competetive price: All powders are factory directly supplied, it's factory price and negotiable.
3. Fast and safe delivery: Your goods will be sent out within 24 hours after payment, tracking number available, customs pass rate ≥99%.
4. Good pre&after-sales service: Any problem please feel free to contact us, we will always be online for you.
High quality, competetive price, fast and safe delivery, good service,that's us! Welcome to contact!
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