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legal anabolic supplements,
sarms anabolic steroids
Healthy Bodybuilding Sarms CAS 1379686-29-9 Sr9011 Effective Weight Loss & Muscle Building Supplement
Name: SR9011 powder
Molecular Weight: 479.03
Melt Point: 242-246℃
Storage Temp:4°C for 1 year
Appearance: white to light yellow Powder
Sarms Sr9011 Description:
SR9011 powder is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. Recommended for use in peroxide cured coatings, sealants, and PCV-based plastisols. Performance properties include: good adhesion, good chemical resistance, good hardness, good heat resistance and high abrasion resistance.
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
Sarms Sr9011 Usage:
SR9011 powder is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 powder alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice.
A new compound called SR9011 increases metabolism, fat burning, and muscle growth in the lab.
Scientists at The Scripps Research Institute (TSRI) have successfully tested a drug, called SR9011, in mice that kickstarts metabolism and results in increased muscle development.
Essentially, it's an exercise regime in a pill.
SR9011 alters the metabolic profile of skeletal muscle in a manner similar to the changes observed animal are endurance trained. Basically, the drug sends a signal to the muscle to tell it to modify its metabolism.
Half of the mice studied showed improved running endurance in terms of both time and distance. What was clearly interesting was that a small, drug-like molecule could increase metabolic rate in skeletal muscle and increase exercise endurance.
Sarms Sr9011 Application:
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.
Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.
Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic
SR9011 powder VS SR9009 powder:
The difference between SR9009 and other diet pills is in its chemistry. SR9011 powder is not an appetite suppressant-as many weight-loss drugs are-and directly works by increasing the metabolic rate of muscle. Your metabolism speeds up and slows down naturally during the day, meaning that sometimes food is used for energy and sometimes it’s stored as fat. By re-synching a dysfunctional metabolic clock, SR9011 powder ensures that food and excess fat are used as energy.
SR9009 and SR9011 powder are attractive as performance-enhancing substances due to their REV-ERB agonist effects and thus circadian rhythm modulation activity. Although no pharmaceutical preparations are available yet, illicit use of SR9009 and SR9011 powder for doping purposes can be anticipated, especially since SR9009 is marketed in illicit products. Therefore, the aim was to identify potential diagnostic metabolites via in vitro metabolic studies to ensure effective (doping) control. The presence of SR9009 could be demonstrated in a black market product purchased over the Internet. Via human liver microsomal metabolic assays, eight metabolites were detected for SR9009 and fourteen metabolites for SR9011 powder by liquid chromatography-high resolution mass spectrometry (LC-HRMS). Structure elucidation was performed for all metabolites by LC-HRMS product ion scans in both positive and negative ionization mode. Retrospective data analysis was applied to 1511 doping control samples previously analyzed by a full-scan LC-HRMS screening method to verify the presence of SR9009, SR9011 powder and their metabolites. So far, the presence of neither the parent compound nor the metabolites could be detected in routine urine samples. However, to further discourage use of these potentially harmful compounds, incorporation of SR9009 and SR9011 powder into screening methods is highly recommended.
AMOUNT OF POWDER AND SOLVENT LIQUID
Preparing a daily dose increases the chances of error. For a 5-day dose, you may take 10mg×5= 50mg of SARM powder and 5ml solvent liquid.
As soon as you get a hold of it, you may prepare a larger quantity for more number of days.
Here’s a step-by-step manual for you to make your SARM journey easier and more fruitful.
Take a pan. Add water and put it on the stove.
Take a beaker. Add solvent liquid to a beaker such as DMSO, Everclear, or PEG-300.
Other derivatives of PEG might make the solution thicker so it’s better to use this one only. You may also use glycerine to improve your taste.
Put the beaker in the warm water pan such that the water doesn’t enter the beaker.
Add your SARM powder and stir it well. The end solution must be clear with no lumps. Some SARM does not dissolve readily or completely.
So shake well before use!
Transfer the solution into the sealed vial. Note that you may use an eyedropper and a microscale for measurement.
The liquid prepared will still taste awful so you will have to get used to the unpleasant flavor.
Now I hope that this step-by-step manual guide is useful for you in the SARM journey. And, honestly, in my opinion, powdered form is a perfect choice. Changing it to liquid form will solve a much greater problem which is the degree of accuracy in dose.
All you have to do now is order your preferred SARM in powder form and start using it!
Q1: Have your Product Quality been Approved by Third Party Lab
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2: How do you treat quality complaint
A: First of all, our QC department will do strict examination of our export products by HPLC, UV, GC ,
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
Q3: Is there any discount
A: Yes, for larger quantity, we always support with better price.
Q4: How long does it take to the goods arrived
A: It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
Q5: Do you have any reshipment policy
we have good after-sale service and re-shipment policy if the parcel lose
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship
Q6 : Can I get a sample
A: Of course. For most products we can provide you a free sample, while the shipping cost should
undertake by your side.
we are a leading manufacturer of steroid raw materials ,.and Peptides
many distributors and labs , bodybuilders from worldwide cooperate with us ,
all speak highly of our safe shipping and goods .
If you require further information please donot hesitate to contact us.
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