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Estrogens Series Steroids 99.9% Powder Chlormadinone Acetate for Hormonal Drugs

Estrogens Series Steroids 99.9% Powder Chlormadinone Acetate for Hormonal Drugs

  • Estrogens Series Steroids 99.9% Powder Chlormadinone Acetate for Hormonal Drugs
  • Estrogens Series Steroids 99.9% Powder Chlormadinone Acetate for Hormonal Drugs
Estrogens Series Steroids 99.9% Powder Chlormadinone Acetate for Hormonal Drugs
Product Details:
Place of Origin: China
Brand Name: Pharmlab
Certification: ISO 9001, USP,GMP
Model Number: 302-22-7
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: negotiable
Packaging Details: Well disguised package with safe new shipping method;As requested.
Delivery Time: Shipment within 24 hours, 3 to 5 days arrived
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: Mass in stock
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Detailed Product Description
Product Name: Chlormadinone Acetate CAS: 302-22-7
Appearance: White Crystalline Powder Grade: Pharmaceutical Grade
MF: C23h29clo4 MW: 404.93
Standard: 99% Shipping: EMS,HKEMS,FEDEX,DHL,TNT,Aramex,etc
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Estrogens Series Steroids 99.9% Powder Chlormadinone Acetate for Hormonal Drugs

 

 

 

Chlormadinone Acetate Specification:

Product Name Chlormadinone Acetate
Chlormadinone Acetate CAS 302-22-7
Chlormadinone Acetate MF C23h29clo4
Chlormadinone Acetate MW 404.93
Apperance white crystalline powder
Grade Pharmaceutical Grade
Packing Discreet package for delivery guarantee!
Assay 99%
Delivery terms HKEMS,DHL,TNT,EMS,Fedex,UPS
Payment Western Union, Money gram, T/T,Bitcoin
 

Estrogens Series Steroids 99.9% Powder Chlormadinone Acetate for Hormonal Drugs 0

 

 

 

Chlormadinone Acetate Description

 

Chlormadinone acetate (INN, USAN, BAN, JAN; sold under brand names including Clordion, Gestafortin, Lormin, Non-Ovlon,Normenon, Verton, and many others) (CMA) is a derivative of progesterone (17α-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione), first synthesized in 1961 and is used as an orally effective progestogen in hormone replacement therapy (HRT), and in combination with ethinyl estradiol (EE) in contraception since 1999. Chlormadinone acetate has a strong progestogenic effect — about one-third higher than that of progesterone — and may vary depending on the previous effect of an estrogen, i.e., estrogens may promote the formation of progesterone receptors and proliferation of the endometrium. Like progesterone, it is anti-estrogenic and has no partial androgenic effect (at the doses used for contraception and HRT). In contrast to progesterone, it has a slight glucocorticoid effect, a pronounced anti-androgenic effect and no anti-mineralocorticoid effect. No pregnancy-maintaining effect of CMA has been demonstrated in humans.


The anti-androgenic effect of CMA is presumed to be the result of both its binding to androgen receptors — competitively inhibiting the effect of endogenous testosterone and dihydrotestosterone — and the competitive inhibition of 5α-reductase. In this respect, dosing of CMA is crucial; agonistic effects are observed when doses are increased from those optimal for an antagonistic effect.

 

Chlormadinone Acetate Application

 

Chlormadinone acetate is a steroidal progestin with additional antiandrogen andantigonadotropic (and thus also antiestrogenic) effects. It is used clinically as a hormonal contraceptive, and in part due to its lowering of estrogen levels, but also for improved effectiveness in contraception, chlormadinone is frequently combinedwith ethinyl estradiol for this purpose.

Chlormadinone acetate has a strong anti-gonadotropic effect, through negative feedback on gonadotropin secretion, and has been used for more than 20 years alone for contraception in arterial risk patients. The clinical and metabolic tolerability of CMA has been demonstrated in numerous clinical studies with duration of treatment of up to 2.5 years.


Chlormadinone acetate (CMA) is a derivative of naturally secreted progesterone that shows high affinity and activity at the progesterone receptor. Chlormadinone acetate has an anti-estrogenic effect and, in contrast to natural progesterone, shows moderate anti-androgenic properties. Chlormadinone acetate acts by blocking androgen receptors in target organs and by reducing the activity of skin 5alpha-reductase. Chlormadinone acetate suppresses gonadotropin secretion and thereby reduces ovarian and adrenal androgen production. Chlormadinone acetate shows high contraceptive efficacy by inhibiting ovulation due to its ability to suppress or disrupt endogenous gonadotropin secretion and, by this, inhibits follicular growth and maturation. In addition, Chlormadinone acetate suppresses endometrial thickness and increases the viscosity of cervical mucus.

 

Packaging & Delivery


1. Professional team for package and shipment.Special way to ship 100grams to 100kg powders at one time to your country.


2. Fast and discreet shipment could be arranged for customs pass Guaranteed.


3. Tracking code 24 hours for customs pass guaranteed.


4. Many kinds of shipment, also can be as your requirement.

 


Our Advantage


1. Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.


2. We have a more profound professional knowledge, you can do a full range of services.


3. Great quality,favorable price and safe transport.


4. Secure and discreet shipment.


5. Parcel can be sent out in 24 hours after payment, express delivery with DHL, EMS, HKEMS, TNT, UPS, Fedex and 24h after-sales service.

 

 

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