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Alkaloid Synephrine CAS 94-07-5 Pharmaceutical Intermediates for Weight Loss
Product Name: Synephrine
Brand Name: Pharmlad
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Specification: USP, BP
MOQ: 10 Gram
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Synephrine, or, more specifically, p-synephrine, is an alkaloid, occurring naturally in some plants and animals, and also in approved drugs products as its m-substituted analog known as neo-synephrine.
p-Synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine. This substance is present at very low concentrations in common foodstuffs such as orange juice and other orange (Citrus species) products, both of the "sweet" and "bitter" variety. The preparations used in Traditional Chinese Medicine (TCM), also known as Zhi Shi, are the immature and dried whole oranges from Citrus aurantium (Fructus Aurantii Immaturus). Extracts of the same material or purified synephrine are also marketed in the US, sometimes in combination with caffeine, as a weight-loss-promoting dietary supplement for oral consumption. While the traditional preparations have been in use for millennia as a component of TCM-formulas, synephrine itself is not an approved OTC drug. As a pharmaceutical, m-synephrine is still used as a sympathomimetic (i.e. for its hypertensive and vasoconstrictor properties), mostly by injection for the treatment of emergencies such as shock, and rarely orally for the treatment of bronchial problems associated with asthma and hay-fever.
It is important to distinguish between studies concerning synephrine as a single chemical entity (and even here it should be borne in mind that synephrine can exist in the form of either of two stereoisomers, d- and l-synephrine, which are chemically and pharmacologically distinct), and synephrine which is mixed with other drugs and/or botanical extracts in a "Supplement", as well as synephrine which is present as only one chemical component in a naturally-occurring mixture of phytochemicals such as the rind or fruit of a bitter orange. Mixtures containing synephrine as only one of their chemical components (regardless of whether these are of synthetic or natural origin) should not be assumed to produce exactly the same biological effects as synephrine alone.
Synephrine main Function
Synephrine has become more popular recent years due to another popular weight loss drug being banned. The drug ephedrine is no longer legally sold in many countries due to the health risks that are associated with taking it. It has been found that synephrine is very similar to ephedrine in many ways and people who take it often show similar side effects. Companies who sell the drug are thought to be exploiting a loop-hole that allows them to sell a drug that’s similar to the banned substance.
1. Applied in food field, it is used as a flavor enhancer and sweetener in a wide variety of
alcoholicbeverage, dessert foods and savory foods.
2. Applied in cosmetics, it can added into toothpaste and mouth wash.
3. Applied in pharmaceutical field, it is mainly used to reducing the bitterness of in form.
4. Applied in Feed Field,Used for livestock feed as a means of reducing feeding time.
Synephrine Recommended Dose
The recommended dose of the drug varies depending on the exact pill taken. A single dose is usually anywhere up to 30 mg although it can be much less than this. For medical use the drug may be used in doses up to 100 mg although it is often injected in this case.
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