Place of Origin: | China |
Brand Name: | Pharmlab |
Certification: | ISO 9001, USP,GMP |
Model Number: | 112809-51-5 |
Minimum Order Quantity: | negotiation |
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Price: | negotiation |
Packaging Details: | Disguised package ; Foil bag |
Delivery Time: | 3-5 work days |
Payment Terms: | Western Union, MoneyGram, T/T, bitcoin |
Supply Ability: | Mass in stock |
Name: | Letrozole | CAS: | 112809-51-5 |
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Grade: | Pharmaceutical | Package: | Well Disguised Package ;Foil Bag |
Purity: | 99% | Appearance: | White Or Light Yellow Crystal Powder |
High Light: | oral steroids bodybuilding,safest anabolic steroid |
Product Name |
Letrozole |
Alias |
Femara |
CAS |
112809-51-5 |
Purity |
99% |
Packing |
foil bag or tin. |
Appearance |
White or light yellow crystal |
Standard |
Enterprise Standard |
Storage |
Shading , confined preservation |
Usage |
Anti-estrogen |
Molecular Fomular |
C17H11N5 |
Molecular Weight |
285.31 |
Molecular Structure |
|
Femara is a third generation aromatase inhibitor. Like most aromatase inhibitors it was developed to fight breast cancer by inhibiting aromatization via the aromatase enzyme. It is similar to arimidex, however femara is much more potent in it's ability and is used primarily when other treatments such as selective estrogen receptor modulators have failed to produce results. This is why the majority of the research about femara has been conducted on post-menopausal women, but of course some of the findings can be translated over for the benefit of athletes.
Femara is intended for use only by women who are no longer of childbearing age. Possible candidates must have already ceased to menstruate. It is often used in patients who have already undergone other cancer treatments, such as radiation, chemotherapy, and used other cancer drugs, like tamoxifen. This nonsteroidal aromatase inhibitor may help prevent any remaining cancer cells from spreading.
Femara is used for the treatment of post-menopause breast cancer. Femara is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body.
Letrozoleis intended for use only by women who are no longer of childbearing age. Possible candidates must have already ceased to menstruate. It is often used in patients who have already undergone other cancer treatments, such as radiation, chemotherapy, and used other cancer drugs, like tamoxifen. This nonsteroidal aromatase inhibitor may help prevent any remaining cancer cells from spreading.
Femara is used for the treatment of post-menopause breast cancer.
Femara is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body. Side effects from include a lowered sex drive and continuous use can lead to lowered lipid function and an impaired immune system.
Tests |
Specifications |
Results |
Appearance |
White or off-white crystaline powder |
White |
Solubility |
Soluble in Chloroform |
Conform |
ldentification |
Maximum absorption in wavelength of 240 nm |
Conform |
Infrared spectrum should be in accordance the dominant peak of contrast |
In accordance with the dominant peak of contrast |
|
Melting points |
182℃-184℃ |
182℃ |
Related substances |
≤0.5% |
0.3% |
Single impurity |
≤0.3% |
0.2% |
Loss on drying |
≤1.0% |
0.8% |
[Assay]C17H11N5 |
≥98.0% |
99.2% |
Conclusion |
Conforms Specifications of Enterprise Standard. |
The general range of Letrozole doses are approximately 1.25mg – 2.5mg daily. There does exist a very large margin for adjustment and user preference when it comes to Letrozole dosages, as each individual should slowly adjust their dose depending on how they feel the body is responding. This is especially so for Letrozole, which is the most powerful and potent AI of the three. Even 1.25mg daily is too much for many anabolic steroid users, and often times the recommended dose is actually 1.25mg every other day, and often can be even less frequent especially considering the half-life of Letrozole is that of 2 – 4 days. These Letrozole doses can easily be adjusted if the user feels it is not working well enough, or if it is reducing Estrogen levels too much.
Letrozole may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use letrozole with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Letrozole may cause dizziness; alcohol, hot weather, exercise, or fever may increase this effect. To prevent dizziness, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of dizziness.
If you may become pregnant, you must use effective birth control while you take letrozole. Women who are going through or have recently gone through menopause may still become pregnant. Talk with your doctor about the use of effective birth control while you take letrozole.
Lab tests, including bone mineral density or cholesterol levels, may be performed while you use letrozole. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Use letrozole with caution in the ELDERLY; they may be more sensitive to its effects.
Letrozole should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: Do not use letrozole if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use letrozole, check with your doctor. Discuss any possible risks to your baby.
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Letrozole as an anti-estrogen is extremely beneficial to breast cancer patients. Many forms of breast cancer actively feed off the estrogen hormone. By inhibiting the production of estrogen, which in turn lowers the amount of circulating estrogen in the body, this has the ability to starve the cancer. For years Nolvadex was the preferred form of treatment for this purpose. Nolvadex actively binds to the estrogen receptor, thereby preventing estrogen from binding. However, it does not inhibit or lower production. Nolvadex is still extremely valuable in breast cancer treatment plans, but many physicians, especially in extreme cases have begun to use AI’s first. Once the cancer is in remission, at this stage a SERM like Nolvadex may replace the AI in an effort to protect against the cancer reappearing.
Undeniably, AI’s like Letrozole are the most effect means at combating estrogenic related side effects. However, they can also have a negative impact on cholesterol. Alone AI’s do not appear to have a strong, negative effect on cholesterol, but when coupled with an aromatizing steroid like testosterone the adverse cholesterol effect is enhanced. For this reason, many will find SERM’s like Tamoxifen Citrate (Nolvadex) should be their first choice in estrogen protection. SERM’s will not negatively affect cholesterol; in fact, SERM’s, while anti-estrogenic, actively act as estrogens in the liver, and in turn, promote healthier cholesterol levels. We’ll look at this in more detail in the side effect section, and while Letrozole can be used without an adverse cholesterol effect, it will take some effort on your part.
Letrozole is used treat early breast cancer in women who have experienced menopause and who have had other treatments, such as radiation or surgery to remove the tumor. It is also used to treat early breast cancer in women who have experienced menopause and who have already been treated with a medication called tamoxifen (Nolvadex) for 5 years.
Letrozole is also used in women who have experienced menopause as a first treatment of breast cancer that has spread within the breast or to other areas of the body or in women whose breast cancer has worsened while they were taking tamoxifen.
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Lead time |
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About 5 working days (Door-to-Door) |
After-sale service |
24/7 Online for any problems |
Contact Person: Moran
Tel: +8613264734726