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| Place of Origin: | China |
| Brand Name: | RAWSGEAR |
| Certification: | ISO 9001, USP,GMP |
| Model Number: | 27262-48-2 |
| Minimum Order Quantity: | negotiation |
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| Price: | negotiation |
| Packaging Details: | Disguised package ; Foil bag |
| Delivery Time: | 3-5 work days |
| Payment Terms: | Western Union, MoneyGram, T/T, Bitcoin |
| Supply Ability: | Mass in stock |
| Product Name: | Levobupivacaine Hydrochloride | CAS: | 27262-48-2 |
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| Other Name: | (S)-(-)-BUPIVACAINE HCL | Appearance: | White Crystalline Powder |
| Shipping Policy: | Sample Order Available | Shipping Methods: | EMS,HKEMS,FEDEX,DHL,TNT,Aramex,ETC |
| High Light: | topical anesthetic drugs,pain killer drugs |
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Levobupivacaine Hydrochloride is the hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property.
Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AbbVie under the trade name Chirocaine.
| Product Name | Levobupivacaine hydrochloride |
| CAS | 27262-48-2 |
| MF | C18H29ClN2O |
| MW | 324.89 |
| Purity | 99% |
| Appearance | white crystalline powder |
| Usage | Local anaesthetics |
| Categories | Pharmaceutical Raw Materials;Active Pharmaceutical Ingredients;API;Inhibitors |
| Synonyms | TIMTEC-BB SBB001337;(S)-(-)-BUPIVACAINE HCL; (S)-(-)-BUPIVACAINE HYDROCHLORIDE; (S)-(-)-1-N-BUTYL-2',6'-DIMETHYL-2-PIPERIDINCARBOXANILID HYDROCHLORIDE; (S)-(-)-1-BUTYL-2-(2,6-XYLYLCARBAMOYL)-PIPERIDINE HYDROCHLORIDE; s-(-)-1-butyl-2',6'-pipecoloxylidide hydrochloride; (s)-1-butyl-2',6'-piperidinecarboxamidemonohydrochloride; (s)-1-butyl-n-(2,6-dimethylphenyl)-2-piperidinecarboxamidemonohydrochloride |
Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.
The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium. This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.
The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.
Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.
Indications are mainly used for surgical epidural anesthesia.Adult for nerve block or infiltration anesthesia, a maximum dose of 150mg. Concentration of the preparation of the solution: surgical epidural block: 0.5% ~ 0.75% 10 ~ 20ml 50 ~ 150mg moderate to all motor block.
| Product Name | Levobupivacaine hydrochloride | ||
| Batch . | 15061201 | Mfg. date | 2016.06.12 |
| Approval Date | 2016.06.23 | Exp. date | 2018.06.01 |
| Description | White Or Almost White Crystalline Powder | Date of Expiry | 2017.12.01 |
| Results Of Analysis Tests | |||
| Test | Analysis Standard | Results | |
| Melting Point | 139~145ºC | 139.5~142.5ºC | |
| Specific Rotation | +55°~ +58° | +57.2° | |
| Loss On Drying | 0.32% | ≤1.0% | |
| Residue On Ignition | 0.03% | ≤0.2% | |
| Assay | 99.36% | 98.0%~101.0% | |
| Conclusion | Be Conform With Enterprise Standard | ||
| Molecular formula | |
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| Tetracaine HCL | CAS 136-47-0 |
| Articaine HCL | CAS 23964-57-0 |
| Levobupivacaine HCL | CAS 27262-48-2 |
| Ropivacaine HCL | CAS 132112-35-7 |
| Ropivacaine Mesylate | CAS 854056-07-8 |
| Dyclonine HCL | CAS 536-43-6 |
| Mepivacaine HCL | CAS 1722-62-9 |
| Chloroprocaine HCL | CAS 3858-89-7 |
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