S-23 CAS 1010396-29-8 SARMs Raw Powder for Muscle Building and Fat Loss

S-23 CAS 1010396-29-8 SARMs Raw Powder for Muscle Building and Fat Loss

WHAT IS S-23?

S-23 demonstrates a markedly strong bond to androgen receptors

S-23 is an modern selective androgen receptor modulator (SARM) with the added interest in its potential for male hormonal contraceptive. It binds to the androgen receptor more strongly than older compounds such as Andarine with a Ki of 1.7nM, and in animal studies it showed both a good ratio of anabolic to androgenic effects, and dose-dependent suppression of spermatogenesis with spontaneous recovery after cessation of research.

Added value for research with pronounced suppression of spermatogenesis

​Not for human consumption

Quick Details

Description

The full name for S23 [structural formula shown below] is (S)-N-(4-cyano-3-trifluoromethyl-phenyl)-3-(3-fluoro,4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide. S23 is closely related to S22.

S-23 is an orally active nonsteroidal SARM with a very high binding affinity to androgen receptors. This makes it stronger than other popular SARMS like Ostabolic (mk-2866) or Andarine (S-4). Therefore, the main effects of S-23 are increased muscle mass, decreased fat mass, and a decrease in the size of the prostate.

Additionally, in a study done on rats a dose equivalent to 15 milligrams (mg) for a 180lb male was shown to also increase bone mineral density, as well as promote muscle mass growth and fat loss. Hence, S-23 is versatile in that it can be used for bulking and for cutting.

S-23: Boosted muscle mass & Reduced fat mass

S23 not only boosted muscle mass, but also reduced fat mass, as studied. SARMs have a bit of a 'soft' image in the doping world. They don't stimulate muscle growth in the way that anabolic steroids do, but many users say that they are safer. There are no studies yet that confirm this suspicion. But that S23 is not one of the safer SARMs - we’d be willing to wager a bottle of BCAAs on that. S23 halts the production of sperm in the testes. In fact it does this so well that the researchers suspect S23 might be a good candidate for a male contraceptive. If this is the case it would probably have to be part of a cocktail that also contains an estradiol analogue, the researchers discovered. The lab animals lost their libido when they were given S23 on its own, and only recovered this when they were given estradiol benzoate together with the S23.

S-23 DOSAGE

S-23 is new to the market, and no recommendation for dose is available. Data shows that a dose of 0.3 mg S23 [human equivalent: 15 mg] leads to an increase in muscle mass, but that the prostate dimensions decreased. But there is no official doses for S23 yet. We will update the dosing information when it is available.

S-23 BENEFITS

S-23 is an orally active nonsteroidal SARM with high binding affinity to androgen receptors that appears to increase muscle mass, decrease fat mass, decrease prostate size, and act as an effective and reversible hormonal male contraceptive in rats.

Data shows that a dose of 0.3 mg S23 [human equivalent: 15 mg] leads to an increase in muscle mass, but that the prostate dimensions decreased. S23 not only boosted muscle mass, but also reduced fat mass.

S23 halts the production of sperm in the testes. In fact it does this so well that the researchers suspect S23 might be a good candidate for a male contraceptive.

Researchers found that treating non-castrated male rats for 14 days with 0.1mg/day or more of this compound, decreased LH levels by 50+%, significantly decreased prostate size, and significantly increased levator ani muscle size. Although the increased muscle growth is a positive sign, the decreased LH levels and prostate size is a big red flag.

S-23 was also found to increase BMD, and reduce fat mass in lab rats. S23 is particularly unique because of its potential as a contraceptive. When non-castrated male rats were treated with 0.1mg/d of S-23 and EB for 10 weeks, LH and FSH levels decreased, 4 of the 6 male rats had no sperm in the testis, and none of the six rat couples experienced pregnancies during mating trials.

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S-23

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