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| Place of Origin: | China |
| Brand Name: | Pharmlab |
| Certification: | ISO 9001 ,USP,GMP |
| Model Number: | 62-44-2 |
| Minimum Order Quantity: | negotiation |
|---|---|
| Price: | negotiation |
| Packaging Details: | 25kg / drum |
| Delivery Time: | 3-5 work days |
| Payment Terms: | T/T, Western Union, MoneyGram, Bitcoin |
| Supply Ability: | Mass in stock |
| Product Name: | Phenacetin | CAS: | 62-44-2 |
|---|---|---|---|
| Purity: | 99% | Shipping Methods: | EMS,HKEMS,FEDEX,DHL,TNT,Aramex,ETC |
| Shipping Policy: | Sample Order Available | ||
| High Light: | topical anesthetic drugs,pain killer drugs |
||
| Melting point | 133-136 °C(lit.) |
| Boiling point | 132 °C / 4mmHg |
| storage temp. | 2-8°C |
| form | powder |
| Water Solubility | 0.076 g/100 mL |
| Sensitive | Hygroscopic |
| Merck | 14,7204 |
| BRN | 1869238 |
| Stability | Stable. Incompatible with strong oxidizing agents, strong acids. |
| CAS DataBase Reference | 62-44-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetamide, N-(4-ethoxyphenyl)-(62-44-2) |
| EPA Substance Registry System | Acetamide, N-(4-ethoxyphenyl)-(62-44-2) |
| Chemical Properties | white crystalline powder |
| Usage | Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens. |
| Usage | glycosylation inhibitor |
| General Description |
Odorless fine white crystalline solid with a lightly bitter taste. Used as an analgesic medicine. |
| Air & Water Reactions | Insoluble in water. |
It is also called acetophenetidins. Having glossy leaflets or scales-like crystals that have no odor or taste.
Melting point 134 ~ 137. Stable in air, soluble in water, slightly soluble in boiling water, slightly soluble in
ether, soluble in ethanol, chloroform. It is formed through the etherification,reduction and Acetylation
reaction of p-chloronitrobenzene. As chloroacetanilide antipyretic and analgesic agent. Suitable for fever,
headache, neuralgia and other drugs as a compound agent.
Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin, low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic effect. Because the enzyme inhibitor make phenacetins not be converted into paracetamol, still showed obvious antipyretic effect,thus the antipyretic effect after the product line not converrt to paracetamol.The mild phenacetisns analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.
Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetis has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treatrheumatoid arthritis (subacute type) and intercostal neuralgia.
| Test Items | Specification | Test Results | ||
| Description | Should comply with the standard | Pass | ||
| Identification | Should be positive reaction | Pass | ||
| P-Phenetidine | Brownish red 4# | Pass | ||
| 4-chloroacetanilide | Should comply with standard | Pass | ||
| Sulphated ash | ≤0.1% | 0.06% | ||
| Melting point | 134ºC to 137ºC | 134ºC to 137ºC | ||
| Appearance | ≥99% | 100.58% | ||
| Conclusion | Complies with BP68 edition | |||
Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin, low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic effect. Because the enzyme inhibitor make phenacetins-Acetate not be converted into paracetamol, still showed obvious antipyretic effect,thus the antipyretic effect after the product line not converrt to paracetamol.The mild phenacetins-Acetate analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.
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