CJC1295 Without DAC Human Growth Hormone Peptide for Muscle Building CAS 863288-34-0

CJC1295 Without DAC Human Growth Hormone Peptide for Muscle Building CAS 863288-34-0

Quick details

Alias: CJC-1295 Acetate; CJC1295(Without DAC);

Sequence:Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(Maleimidopropionyl)-NH2

Cas No.: 863288-34-0

Molecular Formula: C165H271N47O46

Molecular Weight: 3649.30

Purity (HPLC): 98.0%

Appearance: White powder

Single Impurity(HPLC): 1.0%

mino Acid Composition: 10% of theoretical

Peptide Content(N%): 80%(by %N)

Water Content(Karl Fischer): 6.0%

Acetate Content(HPIC): 15.0%

MS(ESI): N/A

Mass Balance: 95.0~105.0%

Specification

CJC-1295 Applications

The DAC technology in the CJC-1295 enables the compound to bind itself covalently with any circulating albumin, after it has been administered through a subcutaneous injection. However, the reason why the half-life could be extended from a few minutes to several days is more profound. The reactive group in the CJC-1295 binds to a peptide through bioconjugation. The peptide then finds a neucleophilic unit within the blood and reacts with it in order to create a firmer bond.

When using any GHRH, it should always be remembered that positive results cannot be achieved overnight. These compounds act steadily over time, and the best results can be achieved slowly, and with a nutritious diet and a proper exercise regime. Also, these peptides are not sex-specific, so they do not have any androgenic effects. They can be used by women in the same dosages that men do.

What is CJC-1295 without DAC and used for?

Modified GRF 1-29 is also known as Mod GRF 1-29, but even more commonly known as CJC-1295 without DAC. It is a protein that is 29 amino acids long and it is a GHRH analogue. CJC-1295 without DAC acts on receptors at the pituitary gland to stimulate the release of Human Growth Hormone.

CJC-1295 without DAC could be referred to more properly as a second generation derivative of GHRH. GHRH is modified to create what is known as Releasing Factor (GRF) 1-29, also known as Sermorelin. GRF 1-29 is then further modified to create Mod GRF 1-29 which is CJC-1295 without DAC.

CJC-1295 without DAC Dosage

Mod GRF 1-29 is typically provided in vials containing 2 mg of lyophylized powder, though the amount can vary. The contents should be reconstituted by adding a convenient amount of sterile or bacteriostatic water. If for example 2 mL is chosen and the dosing of the vial is 2 mg, the resulting solution then has a concentration of 1 mg/mL, or 1000 mcg/mL.

At time of dosing, an insulin syringe is used to draw and then inject the desired amount. In the above example, a 100 mcg dose would require a volume of 0.10 mL, or "10 IU" as marked on an insulin syringe.

Injection may be subcutaneous, intramuscular, or intravenous, according to personal preference. If desired, peptide solutions from other vials, such as a vial of a GHRP product, may also be drawn into the same syringe. This reduces the total number of injections required.

I ordinarily recommend a dosage of 100 mcg Mod GRF at a time, simultaneous with injection of a GHRP. For maximum effect, dosing is preferably three times per day at times of low blood sugar, for example about 30 minutes before a meal, but where use is ongoing, a common use is once per day prior to sleep.

Modified GRF 1-29(cjc1295 w/o DAC)

Dose per injection: 100mcg

Injections per vial: 20 x 100mcg dosages

Amount to Inject: If you have used 1ml of water for mixing then a 100mcg dosage = 0.05ml (or 5 units on Insulin Syringe). If you have used 2ml of water for mixing then 100mcg = 0.10ml (or 10 units) and if you have used 3ml of water for mixing, then 100mcg = 0.15ml (or 15 units).

Injection Frequency:

100mcg injected 1-3 times per day, preferably together with a GHRP Peptide at 100-200mcg.

DAC or no DAC?

As I have just stated above, when a person sees the term CJC 1295 without DAC this is really means that they are looking at MOD GRF 1-29. This tetrasubstitued peptide is a modified version of the original GRF 1-29 peptide better known as Semorelin. Due to the extreme short half life of the original GRF 1-29, chemists were able to modify the peptide to offer a longer biological activity that reduced the metabolic clearance. Although with MOD GRF 1-29 its modification had resulted in a greater peptide bond, the average user will still likely need to inject two to three times a day with a GHRP to get the maximum effectiveness for releasing endogenous growth hormone.

Now when the drug affinity complex (DAC) was added to CJC 1295, it allowed for an even greater possibility to utilize smaller GH pulses (what was once thought of as a bleed) that, when combined with a GHRP, will activate growth hormone stores to release throughout the day and night. When the DAC component was added, this allowed the peptide half-life to be extended to about one week and also provided for steadier blood levels after injection.

Now that we understand how important the DAC factor is, this becomes a much more viable and cost effective way to utilize CJC 1295 with DAC along with a GHRP. The DAC, when added, is able to bind to albumin that circulates the body, literally being able to last for days as it looks for receptors to bind to. So, in short, if you prefer to use shorter spikes of GH release then the use of the MOD GRF 1-29 (CJC 1295 without DAC) is going to be optimal. However, if your prefer fewer injections and still want to unleash your growth hormone stores, then 2-3 times a week injections of CJC 1295 with DAC along with your daily injection of GHRP would be the way to proceed for maximizing growth hormone release.

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