PT - 141 Natural Human Growth Bremelanotide For Treating Sexual Disorders CAS 32780-32-8

PT - 141 Natural Human Growth Bremelanotide For Treating Sexual Disorders CAS 32780-32-8

Basic Information

• Product Name: PT-141
• CAS: 32780-32-8
• MF: C50H68N14O10
• MW: 1025.2
• Single Impurity (HPLC): 1.0%max
• Amino Acid Composition: About 10% of theoretical
• Peptide Content (N%): 80.0% min.
• Water Content(Karl Fischer): 6.0%max.
• Acetate Content (HPIC): 15.0%max.
• Appearance: White powder

Description

PT-141, commonly known as PT141 or Bremelanotide.

PT-141 has been shown in studies to exhibit libido-enhancing effects by activating melanocortin receptors.

PT 141 has been researched extensively for its possible treatment of male sexual dysfunction (erectile dysfunction or impotence), female sexual dysfunction (sexual arousal disorder), hemorrhagic shock and reperfusion injury.

Application

PT141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). PT-141 was developed from the tanning peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis that is known as alpha-Melanocyte stimulating hormone. MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido. Resultantly, PT-141 has been shown in studies to exhibit libido-enhancing effects by activating the melanocortin receptors MC1R and MC4R, but not skin tanning. Melanotan 1 and Melanotan 2 have been researched for their use in protecting against the harmful effects of ultraviolet radiation from sunlight due to their melanogenesis-stimulating properties.

PT-141 is a potential remedy for the treatment of sexual dysfunction.specifically, male erectile dysfunction.

Studies have shown that PT-141 does not act on the vascular system like former compounds,but allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation. PT-141 is a melanocortin based peptide that has shown effectiveness in clinical studies on both male and female rats. Male rats have shown erectile response with doses as low as 1-2 mgs whereas most female rats have shown positive results with higher doses around 2-3 mgs. While the dosage requirements tend to be higher for female rats, the observable results in female rats tend to be stronger

.

How to make the liquid PT-141

Bacteriostatic water is the recommended solvent here. To mix the vial with bact water, take one syringe (BD Ultrafine II 1cc or 1/3 cc are excellent and I recommend them) and grab your vial of bacteriostatic water. If using a 1 cc syringe (100 units), use the syringe to withdraw 1 full ml (1cc) and inject that into the vial of PT-141 through the rubber. Be sure to aim the needle towards the glass, so that it will trickle down and not harm the peptide. Swirl the vial to thoroughly mix and let the peptide dissolve. The key here is to be gentle. Say you had the vial of PT-141 stored in the freezer, move the vial of PT-141 to fridge for an overnight stay. Then you are ready the next day to reconstitute the same temperature refrigerated bact water with the PT-141 in the most efficient manner.

The dosage of PT-141

Light PT-141 dosing (250mcg-500mcg)
Common PT-141 dose (~1mg injected subq)
Large PT-141 dose (~2mg)
Taking 2-4 hours before game time is ideal

How to store PT-141

The lyophilized powder (freeze dried state) can be stored in the freezer or refrigerator. Once reconstituted (mixed with water) it will be good for a month in the refrigerator before it begins to degrade.

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