CAS 164656-23-9 Male Enhancement Drugs Dutasteride / Avodart For Hair Loss Treatment

  Male Enhancement Steroids Dutasteride / Avodart CAS 164656-23-9 For Hair Loss Treatment

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Description

Dutasteride (trademark name Avodart) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). Used for benign prostatic hyperplasia; however, it increases the risk of erectile dysfunction and decreased sexual desire.

Dutasteride useful for the symptoms of benign prostatic hyperplasia (BPH); colloquially known as an "enlarged prostate". In those who are being regularly screened 5-alpha-reductase inhibitor (finasteride and dutasteride) reduce the overall risk of being diagnosed with prostate cancer however there is insufficient data to determine if they have an effect on the risk of death and may increase the chance of more serious cases.

COA

Application

Dutasteride is marketed pharmaceutically as Avodart, Avidart, Avolve, Duagen, Dutas, Dutagen, Duprost. For unknown reasons, early clinical trials for dutasteride were abruptly ceased in 2002, then continued later.

Dutasteride is a 5-alpha-reductase inhibitor, meaning it blocks the action of the 5a-reducatse enzymes, that are responsible for 5a-reducing (converting) testosterone into dihydrotestosterone (DHT) by the addition of a double hydrogen bond.

Dutasteride inhibits both isoforms of 5a-reductase, therefore preventing the conversion of testosterone into dihydrotestosterone. This makes Dutasteride a reasonable treatment for Male Pattern Baldness. Of course, when you convert less Testosterone into Dihydrotestosterone, you increase testosterone levels by default (less conversion).

Dutasteride, at 2.5mgs/day is roughly 1.5x more effective than Finasteride at 5mgs/day, at treating hair loss (both halting it as well as regrowing it). In addition, Dutasteride can be used successfully at that same dose to treat prostate enlargement, and a lesser known effect of Dutasteride (again, at that same dose) use is to treat Acne caused by an overabundance of androgens in the body.

For the steroid using athlete suffering from DHT-related side effects, Dutasteride may be the answer. Hairloss, Acne, and prostate growth can all (potentially) be completely halted with the use of this product. Unfortunately, DHT is not all bad, and you potentially lose some muscle hardness (an amorphous quality if ever there is one), and even some of the other qualities we like from our androgen use.

Alsosince this only prevents the 5a-reduction of the androgens subject to that conversion into a dihydro form of themit will likely do nothing to stop hairloss or other symptoms caused entirely by the use of the androgens in the DHT family.

This class of medications increases rates of erectile dysfunction (with between 5% and 9% developing problems after starting their use). This is linked to lower quality of life and can cause stress in relationships. There is also an association with lowered sexual desire. It has been reported that these adverse sexual side effects may persist even after discontinuation of the drug. The FDA has added a warning to dutasteride about an increased risk of high-grade prostate cancer.

While the potential for positive, negative or neutral changes to the potential risk of developing prostate cancer with dutasteride has not been established, evidence has suggested it may temporarily reduce the growth and prevalence of benign prostate tumors, but could also mask the early detection of prostate cancer.

The primary area for concern is for patients who may develop prostate cancer whilst taking dutasteride for benign prostatic hyperplasia, which in turn could delay diagnosis and early treatment of the prostate cancer, thereby potentially increasing the risk of these patients developing high-grade prostate cancer.

Dutasteride Effect

When bodybuilders use anabolic-androgenic steroids, it can speed up head hair loss. This is due to increased hormones in the body. The more testosterone, the more conversion to DHT in the body. In addition, running DHT derivatives such as masteron, winstrol, or proviron will further increase DHT. To combat this, bodybuilders have experimented with 5a-reductase inhibitors, such as dutasteride, to protect their existing hair and even re-grow more. However, this can come at a price and a myriad of side effects.

Dosage and Half-Life

A dosage of 2.5mgs per day is a popular starting point among bodybuilders. Most guys are splitting the dose into AM/PM, but that's not necessary. The half-life of dutasteride is very long - up to 5 weeks. So, you can dose it EOD (every other day) or longer if you wish.

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