|Place of Origin:||China|
|Certification:||ISO 9001, USP,GMP|
|Minimum Order Quantity:||10g|
|Packaging Details:||Well disguised package ; Plastic drum with safe shipping|
|Delivery Time:||3~5 work days|
|Payment Terms:||Western Union, MoneyGram, T/T, Bitcoin|
|Supply Ability:||Mass in stock|
|Product Name:||Acitretin||Other Name:||Etretin|
|Melting Point:||228-230°C||Shipping Time:||3-5 Work Days|
|Delivery Express:||EMS,DHL,UPS,TNT,FedEX||Chemical Properties:||Crystalline Solid|
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Pharmaceutical Raw Materials Acitretin For Antipsoriatic CAS 55079-83-9
Product Name :Acitretin
Synonyms: retinoidetretin,(all-e)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraen;6,8-nonatetraenoicacid,3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-4;all-trans-3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetra;all-trans-etretin;retinoidetretin;ro10-1670;(E)-9-(4-METHOXY-2,3,6-TRIMETHYLPHENYL)-3,7-DIMETHYL-2,4,6,8-NONATETRAENOIC ACID;etretin
Storage temp. 2-8°C
Usage: A synthetic retinoid which is the major metabolite of etretinate (E938000).
Acitretin is a second generation retinoid. It is taken orally, and is typically used for psoriasis. It is a metabolite of etretinate, which was used prior to the introduction of acitretin. They induce keratinocyte differentiation and reduce epidermal hyperplasia.
Acitretin is the least toxic systemic treatment for psoriasis. It is an oral retinoid of choice used in the treatment of severe resistant psoriasis. It binds to nuclear receptors that regulate gene transcription.
Acitretin was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days.
Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments.
It binds to nuclear receptors that regulates gene transcription. They induce keratinocyte differentiation and reduce epidermal hyperplasia, leading to the slowing of cell reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after 2 to 4 weeks or longer.
Patients that have received the medication are advised against giving blood for at least 3 years due to the risk of birth defects.
Acitretin is noted for the possibility of severe birth defects and should not be used by pregnant women or women planning to get pregnant within 3 years following the use of acitretin. Sexually active women of childbearing age who use acitretin should also use at least 2 forms of birth control concurrently. Men and women who use it shouldnot donate blood for 3 years after using it, because of the possibility that the blood might be used in a pregnant patient and cause birth defects. In addition, it may cause nausea, headache, itching, dry, red or flaky skin, dry or red eyes, dry or chapped lips, swollen lips, dry mouth, thirst, cystitis acne or hair loss.
|Description||A yellow or greenish-yellow,
|Identification||Shall comply||All comply|
|Loss on drying||≤0.5%||0.1%|
|Assay (on dried basis)||98%to102.0%||99.8%|
|Conclusion||The results conforms with EP6.0 standards|
We do understand that you will be worried about our packing methods before you tried or knew us, while we are making the real deal and we do know how customs works.
We have professional team for special disguised package, no word concern steroid will be whown on the parcels, the pass custom rate is more than 99%.
Before we could be able to offer some details of our package and shipping methods, and it is better to discuss by mail , skype or whatsapp.
Our company owns a professional and efficient team for packing with our best discrete or stealth packages. Orders will be sent out within only one working day after payment.Package details and tracking number will be sent to you.Shipment by DHL, TNT, FedEx, HKEMS, UPS, ,EUB,ETK and so on.
It usually takes 4 to 7 days or 7 to 10 days by some other express courier; it will be 15 to 20 days by slow post.
Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
We will stack on the parcels until you get them on hand so that you do not need to spare time on this.
1. 24 hour deliver after payment .
2. High purity and good price.
3. best free resend policy .
4. professional warehouse and reliable express agent with disguise package.
5. over 98% passing rate .
6. top quality is our life .
7. 24h after-sales service.
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