S-4 / Andarine SARMs Raw Powder CAS 401900-40-1Treatment For Muscle Wasting

        SARMs Raw Powder S-4 / Andarine CAS 401900-40-1Treatment For Muscle Wasting

Basic Info

Model NO.: 401900-40-1

Product Name: S-4 (Andarine,GTX-007)

Appearance: Pale Yellow Powder

Suitable for: Elderly, Adult

Purity: >99%

Minimum Order Quantity: 10 G

Function: Muscle Wasting Treatment

Powder: Yes

State: Solid

Delivery Time: Within 24 Hours Upon Receipt of Payment

MW: 441.36

MF: C19H18F3N3O6

Storage: at 20°C 2 years

Trademark: Pharmlab

Origin: China

Quick Detail

What is S-4

As a research chemical, S-4 belongs to a class of chemicals known as SARMS or selective androgen receptor modulators.Like typical androgens, SARMS bind to the androgen receptor however SARMS create selective anabolic activity.

Compared to testosterone and other anabolic steroids and pro hormones, the advantage of SARMS such as S-4 is that they do not have androgenic activity in non-skeletal-muscle tissues.

S4 was designed for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy, using the non-steroidal androgen antagonist bicalutamide as a lead compound.As an orally active partial agonist for androgen receptors, S-4 is effective in not only maintaining lean body mass but actually increasing it.

How does it work

Selective androgen receptor modulators (SARMS) bind to the androgen receptor and demonstrate osteo (bone) and myo (muscular) anabolic activity.

Binding and activation of the Androgen receptor alters the expression of genes and increases protein synthesis which ultimately builds muscle.

SARMS such as S4 can cause muscle growth in the same manner as steroids, however unlike testosterone and other anabolic steroids, SARMS (as nonsteroidal agents) do not produce the growth effect on prostate and other secondary sexual organs.

SARMS not only represent a new potential treatment option for a wide spectrum of conditions such as muscle wasting diseases (from age-related to AIDS or cancer-related), but they also have immense potential for muscle building for Bodybuilders, fitness and athletes.S-4 in particular binds to the androgen receptor in muscle and bone to a third of the affinity of Testosterone.

Description

Andarine (GTx-007, S-4) is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy, using the non-steroidal androgen antagonist bicalutamide as a lead compound.

S-4 belongs to a class of chemicals known as SARMS or selective androgen receptor modulators. Like typical androgens, SARMS bind to the androgen receptor however SARMS create selective anabolic activity.Compared to testosterone and other anabolic steroids and pro hormones, the advantage of SARMS such as S-4 is that they do not have androgenic activity in non-skeletal-muscle tissues.

In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.

Application

Andarine is an orally active partial agonist for androgen receptors. It is less potent in both anabolic and androgenic effects than other SARMs. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.

This suggests that it is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but it spartial agonist effects at androgen receptors prevent the side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH.

Medical Usage

Losing Bodyfat (Cutting)

Certain steroids are considered "cutting" steroids such as Winstrol and Anavar. These steroids don't offer too much in large gains in muscle mass but are very effective in leaning out the body. The SARM S-4 has very similar properties.As S-4 shows this binding affinity to the AR, it demonstrates the similar fat burning effects. S-4 also shows a decrease in LPL (lipoprotein lipase) which is an enzyme that causes lipid accumulation.

S-4 also fits into a cutting protocol for the concurrent reduction in body fat with maintenance of muscle mass in a hypocaloric environment.

As S4 has both anabolic and androgenic effects in muscle tissue, it will not only help with fat loss, but maintain and even increase muscle mass when cutting.S-4 causes increases in vascularity and promote a very nice, "quality", hard look to the users muscles, with little or no water retention.In this way S-4 can be compared to Winstrol, without the harsh hair loss or extreme adverse effects on cholesterol.

Another advantage S-4 offers for cutting is that it doesn't give the painful pumps associated with other popular steroids/Prohormones. Back and calf pumps are particularly detrimental for cutting as it limits the ability to perform cardio.

Strength gains and Lean mass Gains

Due to its androgenicity in muscle tissue, S-4 is a good agent for increases in strength without bloat and large increases in weight.Dosing at 50mg+ is the sweet spot for such gains.

Also, like the oral steroid Anavar (Var) weight gain with S4 may not be that great in comparison to bulking steroids such as deca or Superdrol, but what the lean mass and strength gained during the cycle is kept and not lost after the cycle.

With all dosing protocols, as the half life of S-4 is 4 hours, splitting up the dose into multiple applications is advised.

How to use S4 safely

To negating any side effects, S-4 should be dosed at 5 days on 2 off at 50mg. If you go above 50mg you will lose some night vision if the quality of S4 you got is good. S-4 has a very short half life, 2.6 hours, so it would be perfect to use as a pulse, 3 times a week 2 hours before training should give excellent strength and hardening results. Both those protocols will reduce the yellow eye, and night vision problems.

Remember, a PCT (post cycle therapy) should be always carried out after using S4.

If you want the effects faster, the recommended dosage for cutting is 50 mg for 6-8 weeks. It should be used every day then take 2 days off for the duration. Taking S-4 daily for the length of the cycle can lead to obvious changes by eyesight.

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