Place of Origin: | China |
Brand Name: | Pharmlab |
Certification: | ISO 9001, USP,GMP |
Model Number: | 51-05-8 |
Minimum Order Quantity: | 10g |
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Price: | negotiation |
Packaging Details: | Disguised package ; Foil bag |
Delivery Time: | 3-5 work days |
Payment Terms: | Western Union, MoneyGram, T/T, bitcoin |
Supply Ability: | Mass in stock |
Product Name: | Procaine Hydrochloride | Other Name: | Procaine HCL |
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Melting Point: | 155-156 °C(lit.) | Storage Temp.: | Room Temp |
Boiling Point: | 195-196°C 17mm | Delivery: | Parcel Can Be Sent Out In 24 Hours After Payment |
High Light: | topical anesthetic drugs,pain killer drugs |
Healthy Local Anesthetic Drugs Procaine Hydrochloride For Anti-Inflammatory
Quick Detail:
Product Name : Procaine Hydrochloride
Synonym: Aminocaine, anadolor, anesthesol, anestil, atoxicocaine, Benzoicacid,4-amino-,2-(diethylamino)ethylester,monohydrochloride, benzoicacid,p-amino-,2-(diethylamino)ethylester,monohydrochloride
Appearance: white crystalline powder
Purity: 99.9%
CAS: 51-05-8
Molecular formula: C13H21ClN2O2
Molecular weight: 72.77
Storage: Shading, confined preservation
Usage: Procaine hydrochloride is a kind of local anesthetics, for local anesthesia, nerve block etc, can block the conduction of nerve fibers with anesthetic effect, strong function, low toxicity, and no addiction, but the skin, mucous membrane penetration force is weak, not suitable for surface anesthesia, clinically used to infiltration, spine and conduction anesthesia.
Trademark: Pharmlab
Origin: China
Introduction
Procaine hydrochloride is a salt of the compound Procaine. Procaine is a noted sodium channel blocker with a variety of inhibitory effects. In skeletal muscle, Procaine has been reported to inhibit calcium-induced calcium release (CICR). Procaine is also noted to act as a DNA methylation inhibitor and to cause demethylation and reactivation of methylation-silenced genes such as RARβ and GSTP1. WIF-1 is noted to be reactivated in a cancer cell line and to downregulate the Wnt canonical pathway. In studies utilizing a neuroblastoma cell line (SHEP), Procaine is reported to induce neuronal apoptosis in a manner correlated with lipid solubility of the compound. In an adult mouse muscle cell line (HEK293), the presence of procaine is reported to potently inhibit nicotinic acetylcholine receptors. Procaine is available alone (sc-296134) and in its salt form as Procaine HCl (sc-250776).
Description
Procaine hydrochloride is a topical anesthetic, which can block the nerve fiber conduction temporarilyand has a narcotic effect,strong effect, low toxicity, and non-addictive, but on the skin, mucosal penetration is weak, unsuitable for surface anesthesia, patients are used for infiltration, conduction and spinal anesthesia.
White fine needle crystal or crystalline powder at room temperature, no smell, taste slightly bitter and Ma, soluble in water, soluble in ethanol, slightly soluble in chloroform, almost insoluble in ether. Procaine hydrochloride ester bond structure can be hydrolyzed to produce amino acid and diethylaminoethanol, under certain conditions, the amino acid may be further decarboxylated toxic aniline.
The structure of procaine hydrochloride with aromatic primary amino, easy oxidation discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation discoloration. The aqueous solution was stable in pH3.0~5. So preparation of procaine hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and strictly control the sterilization temperature and time. to 100 ℃ steam sterilization 30min circulation is appropriate, and should pay attention to shading, sealed save.
The product structure of aromatic primary amino group in dilute hydrochloric acid can generate diazonium salt with sodium nitrite, coupling reaction occurs when add alkaline β-naphthol, generating azo compounds scarlet.
Application
Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
COA
Product name | Procaine HCl | |
Appearance | White crystalline powder | |
Assay (C13H20N2O2·HCl) | 99.0% to 101.0% | 99.5% |
Melting point | 153~158ºC | 156.5~157.0ºC |
Heavy metals | ≤20ppm | <5ppm |
Acidity | ≤0.02N NaOH 0.5ml | 0.3ml |
Chromatographic purity | Secondary spots≤0.5%,sum≤1.0% | Conforms |
Loss on drying | ≤1.0% | 0.06% |
Residue on ignition | ≤0.15% | 0.03% |
Bacterial endotoxins | ≤0.6EU/mg | <0.6EU/mg |
Our commitment:
1. Quality assurance
With our years of experience, advanced technology and continuous research, our quality is to fully meet the needs of the market to meet the requirements of customers, many customers use our products, we believe that the product is very good. Whether it is a powder, or liquid, yes, we all know, our liquid better.
2. Safe transportation
Our mode of transport is taken according to each country's situation is different transportation, while our packaging, according to the latest customs situation, constantly updated, improved our packaging, we guarantee that you receive it within 3-5 to your product.
3. The product diversity
Our products are powders and liquids, yes, brothers, the effect of the liquid is very good, but many people do not use liquid, so you are very lucky, you buy our powder, we can tell you the method of making the liquid If you buy a liquid, we will tell you how to filter. We absolutely guarantee that you can very safely use our products
4. High quality service
Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%, As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.
Additional information | |
Payment terms | Western union , Money gram, Bank transfer and Bitcoin |
Min order quantity | 10grams |
Delivery | Sent out within 24 hours after payment confirmed |
Lead time | 3-5 days |
Packaging | Disguised package or as required |
Origin | China |
Shipping | Express Courier(EMS,DHL,UPS,TNT,FedEX) |
Discount | Multiple items ordered one time |
Larger quantity of each item |
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