Crystalline Anabolic Steroids Powder , Prilocaine Pain Killer Powder 721-50-6

Local Anesthetic Drugs powder Prilocaine for Pain Killer Intravenous Regional Anaesthesia

Quick detail

Product name: Prilocaine

CAS: 721-50-6

Appearance: white powder

purity: 99%

Trademark: Pharmlab

Original: China

Grade: Pharmaceutical grade

Package: Disguised package ; Foil bag

Delivery date: 3-5 work days

Certificate: ISO 9001, USP,GMP

Payment: Western Union, MoneyGram, T/T, bitcoin

Shipping: EMS,HKEMS,EUB,ETK,FEDEX,DHL,UPS,Aramex,ETC

Policy: Re-Shipping Policy

MF: C13H21ClN2O
 

MW: 256.77
 

EINECS: 217-244-0

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Product description

Promacaine is a local anesthetic for aminamides. Prilocaine is commonly used in dentistry. Placaine is also often used in combination with lidocaine for skin anesthesia (lidocaine / propranolol or EMLA) for the treatment of paresthesia and other diseases.

Overview of local anesthesia

Local anesthesia is a substance that causes sensory loss only in its application area without affecting consciousness. Most local anesthetic structures have an amino ester or aminoamide group attached to a hydrophilic (secondary or tertiary amine) and a hydrophobic group (aromatic compound) on the other side. The ester can be hydrolyzed by the enzyme to the cholinesterase into PARA-aminobenzoic acid. Amides are stable for long-term and more systematic distributions. Esters include prochlorocene, Novos, Nesacaine, Pontocaine, Benzocaine, tetracaine. Amides include Xylocaine, Carbocaine, Prilocaine (Citanest), Bruaine, and Duranest.

Procaine is a local anesthetic of the aminoamide type prepared by Claes Tegner and NilsLöFgren. In its injectable form (trade name Citanest), it is commonly used in dentistry. It is also often used in combination with lidocaine for skin anesthesia (lidocaine / propylamine or EMLA) for the treatment of paresthesia and other diseases. Because of its low cardiac toxicity, it is commonly used for intravenous anesthesia (IVRA).

Product application

Premarin is a local anesthetic for anesthesia's skin and tissues and cycles; this drug can usually be provided as a topical application and comma cream; but it may also be available in injectable form and comma; Training professionals and time management; its effect is not immediate and comma; but once a person experiences related numbness, it may last for hours; during this time and comma is important to pay attention to her health care provider The advice so that she can avoid harming yourself and during the period;

Health care providers use propranolol to imply that they manage the place of injection or carry out certain procedures and periods of feeling; this drug is considered to be a local anesthetic because it is usually applied to the area of ​​need and cycle; for example & comma if the dentist Use it and the comma he may inject the drug into his work area and the gingival near the periodic location;

In addition to injectable forms and commas, this drug can also be used as a cream and a period of time; cream is suitable for a particular area and period; injections and commas may take longer to take effect; its effects may be more limited and cycle; In the case of commas, once numbness begins, it may last for hours.

Prilocaine local anesthesia is an anesthetic (anesthetic). It can stop your body's nerve signal.

Prilocaine is used locally for anesthesia to the surface of the skin or penis or vagina to prepare a medical procedure or to relieve the pain of inserting a medical device such as a tube or a speculum.

Usage and synthesis

Placaine belongs to the amide local anesthetic drug, its anesthetic intensity and speed and lidocaine similar, but the duration is longer, the vasodilator effect is weak. It is less toxic than lidocaine. Clinical for local anesthesia, especially for the treatment of patients who do not allow the use of adrenaline.

Pharmacology

Its 3% solution with 2% lidocaine narcotic drugs has similar local anesthetic efficacy with adrenaline. The starting time is about 6 ~ 7min, the duration of about 1.5 ~ 2h. It has a strong penetration through the mucosa. The effect of adrenaline is slightly longer. PPB is 55%, T1 / 2 is about 1.5h. Its metabolite nitrosotoluene can oxidize hemoglobin to form methemoglobin, metabolized by the liver. It can be transported to the fetus through the placenta.

Adverse reactions

Once the use of more than 600mg, redness, tachycardia, headache, dizziness, weakness and other methemoglobinemia.

note

Anemia in patients with congenital or acquired methemoglobinemia, respiratory failure or heart failure and hypoxia should be disabled. Prohibited for obstetric anesthesia.

Dosage

Infiltration Anesthesia: 0.5% to 1% solution for a duration of 1 to 1.5 hours.

Nerve block anesthesia: Use 1% to 2% solution for 2-3 hours.

Epidural anesthesia: the use of 10 ~ 30 mL of 1.5% ~ 1% solution, the role of time 2.5 ~ 3.5 hours. Using a maximum dose of 600 mg.

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