Medical Antipruritic Drugs Pramoxine Hydrochloride Local Anesthetic Pramoxine HCL

Medical Antipruritic Drugs Pramoxine Hydrochloride Local Anesthetic Pramoxine HCL

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Pramoxine Hydrochloride Description 1

Pramoxine Hydrochloride is a topical anesthetic and used as an antipruritic too. Chemical name is p-n butoxyphenyl gammamorpholinopropyl ether hydrochloride. During research, Pramoxine Hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially great topical local anesthetic agent. Pharmacologic study revealed Pramoxine Hydrochloride to be very potent and of low acute toxicity, well tolerated by most mucous membranes and of a low sensitizing index. Pramoxine Hydrochloride reduces the permeability of neuronal membranes to sodium ions, blocking initiation and conduction of nerve impulse. Depolarization and repolarization of excitable neural membranes is thus inhibited by Pramoxine Hydrochloride, leading to the numb sensation.

The high potency and low acute and sub-acute toxicity of Pramocaine have popularized its usage in over-the-counter itching creams and sunburn lotions. It may also be used in treating rectal irritations. The drug is sometimes administered in a spray or wipe form.

Pramocaine works by lowering the permeability of neuron membranes to sodium ions. This blocks the initiation and conduction of the nerve impulses that cause sensations of pain. The application of Pramocaine is usually prescribed 3-4 times daily. Although allergic reactions are uncommon, they may sometimes manifest in the form of dryness, burning, stinging, bleeding, hives, skin rash, itching and swelling. This medication should be stored in an airtight container out of reach of children.

Pramoxine description 2

Pramoxine is an anesthetic, or "numbing medicine." It works by interfering with pain signals sent from the nerves to the brain.

Pramoxine topical (for the skin) is used to treat pain or itching caused by insect bites, minor burns or scrapes, hemorrhoids, and minor skin rash, dryness, or itching. Pramoxine topical is also used to treat chapped lips, and pain or skin irritation caused by coming into contact with poison ivy, poison oak, or poison sumac.

Pramoxine topical may also be used for purposes not listed in this medication guide.
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely, and you may have none at all.

You should not use this medication if you are allergic to pramoxine.

Pramoxine Hydrochloride Specification

Use

Pramoxine is used to temporarily relieve itching and pain caused by minor skin irritation such as minor burns/cuts/scrapes, sunburn, eczema, insect bites, cold sores, or rashes from poison ivy, poison oak, or poison sumac. Some products containing pramoxine are also used to temporarily relieve the itching and discomfort from hemorrhoids and certain other problems of the genital/anal area (such as anal fissures, itching around the vagina/rectum).

Pramoxine belongs to a class of drugs known as local anesthetics. It works by numbing the skin to block the feelings of pain and itching.

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Tags: Pramoxine Hydrochloride, Pramoxine HCL, Antipruritic Drugs, Local Anesthetic