|Place of Origin:||China|
|Certification:||ISO 9001, USP,GMP|
|Model Number:||CAS: 51-05-8|
|Minimum Order Quantity:||1kg|
|Packaging Details:||Foil bag ; 25kg/drum ; Disguised package|
|Delivery Time:||3~5 work days|
|Payment Terms:||Western Union, MoneyGram, T/T, Bitcoin|
|Supply Ability:||Mass in stock|
|Product Name 1:||Procaine Hydrochloride||Other Name:||Procaine HCl|
|CAS No:||51-05-8||Appearance:||White Or Off White Crystalline Powder|
|Catagory:||Local Anesthetics||Usage:||Anti Paining|
pain killer powder,
pain killer drugs
Local Anesthetic Drugs Procaine Hydrochloride Procaine HCl For Anti Inflammatory
1. Quick detail
Product name: Procaine hydrochloride ;Procaine HCl
Appearance:white crystalline powder
Usage:Local anesthesic ;Procaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry.
2. Related products:
Benzocaine base: / benzocaine /benzocaine/ procaine / lidocaine / lidocaie hcl / procaine hcl
CAS No.: 94-09-7
Appearance: White Crystal Powder
Usage: Local anesthetic.
Standard: USP/BP standard
Chemical Name: Lidocaine
Molecular Formula: C14H22N2O
Formula Weight: 234.34
CAS No.: 137-58-6
Usage: Local anesthetics
Peoduct name: Lidocaine hydrochloride
Melting point: 350.8° C at 760 mmHg
Usage: Local anesthetics, antiarrhythmic drugs, used for a variety of anesthesia and rapid ventricular arrhythmia
Product name: Procaine
CAS No.: 59-46-1
Appearance: White Crystalline Powder
Place of Origin: China
Usage: Local anesthetics
3. Procaine HCl Specification
|Product name||Procaine HCl|
|Appearance||White crystalline powder|
|Assay (C13H20N2O2¡¤HCl)||99.0% to 101.0%||99.5%|
|Acidity||≤0.02N NaOH 0.5ml||0.3ml|
|Chromatographic purity||Secondary spots≤0.5%,sum≤1.0%||Conforms|
|Loss on drying||≤1.0%||0.06%|
|Residue on ignition||≤0.15%||0.03%|
4. Procaine HCl description :
Procaine hydrochloride is a local anesthetic, can temporarily block the conduction of nerve fibers with anesthetic effect, strong role, low toxicity, and no addiction, but the skin, mucous membrane penetration is weak, not suitable for the surface Anesthesia, clinical mainly used for infiltration, spinal and conduction anesthesia.
White needle-like crystalline or crystalline powder at room temperature, odorless, taste slightly bitter and Ma, soluble in water, soluble in ethanol, slightly soluble in chloroform, almost insoluble in ether. Hydrochloric acid procaine structure in the ester bond can be hydrolyzed to generate amino acid and diethylamino ethanol, under certain conditions, p-aminobenzoic acid can be further decarboxylation to produce toxic aniline.
The structure of procaine hydrochloride with aromatic primary amino, easy oxidation discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation discoloration. The aqueous solution was stable in pH3.0 ~ 5. So preparation of procaine hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and strictly control the sterilization temperature and time. to 100 ℃ steam sterilization 30min circulation is appropriate, and should pay attention to shading, sealed save.
The product structure of aromatic primary amino group in dilute hydrochloric acid can generate diazonium salt with sodium nitrite, coupling reaction occurs when add alkaline β- naphthol, generating azo compounds scarlet.
5. Applications of procaine
Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine LED to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.
Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase, which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.
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7. Local Anesthetic Drugs lists
|Propitocaine hydrochloride||CAS: 1786-81-8|
|Tetracaine hydrochloride||CAS: 136-47-0|
|Procaine hydrochloride||CAS: 51-05-8|
|Pramoxine hydrochloride||CAS: 637-58-1|
|Proparacaine hydrochloride||CAS: 5875-06-9|
|Benzocaine hydrochloride||CAS: 23239-88-5|
|Lidocaine hydrochloride||CAS: 73-78-9|
|Articaine hydrochloride||CAS: 23964-57-0|
|Levobupivacaine hydrochloride||CAS: 27262-48-2|
|Ropivacaine hydrochloride||CAS: 132112-35-7|
|Dibucaine hydrochloride||CAS: 61-12-1|
|Bupivacaine hydrochloride||CAS: 14252-80-3|
Tags: Procaine Hydrochloride, Procaine HCl, Benzocaine facotry, Ship benzocaine to UK 99% safe
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