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| Place of Origin: | China |
| Brand Name: | RAWSGEAR |
| Certification: | ISO 9001 ,USP,GMP |
| Model Number: | 846589-98-8 |
| Minimum Order Quantity: | 10grams |
|---|---|
| Price: | negotiation |
| Packaging Details: | Disguised pacakge ; Foil bag |
| Delivery Time: | 3-5 work days |
| Payment Terms: | T/T, Western Union, MoneyGram, Bitcoin |
| Supply Ability: | Mass in stock |
| Product Namr: | Lorcaserin Hydrochloride | Other Name: | Lorcaserin HCl |
|---|---|---|---|
| Monoisotopic Mass: | 231.058 G/mol | Grade: | Pharmaceutical Grade |
| High Light: | weight stripping steroids,fat shredding steroids |
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Basic Info.
English name: Lorcaserin hydrochloride
English Synonyms: (1R) -8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine hydrochloride; APD 356; APD-356; UNII-0QJF08GDPE; Lorcaserin HCl; (R) - 1H-3-Benzazepine, 8-Chloro-2,3,4,5-Tetrahydro-1-Methyl-, Hydrochloride
CAS: 846589-98-8
Assay: 99%
Appearance: white powder
Formula: C11H14ClN·ClH
MW: 232.1525
Trademark: Pharmlad
Origin: China
Export Markets: Global
Description
lorcaserin hydrochloride is a serotonin 2C receptor agonist. It has been shown to decrease food consumption and promote satiety by selectively activating serotonin 2C receptors in the brain.Belviq is specifically indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in clinically obese adults and overweight adults with at least one weight-related comorbid condition.
Lorcaserin is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life. Lorcaserin belongs to a class of drugs known as serotonin receptor agonists. It is thought to work by affecting a certain part of the brain that helps control your appetite.
Application
Lorcaserin hydrochloride is an agonist of the 5-HT2C receptor and shows effectiveness at reducing obesity in animal models and humans. Further, 5-HT2C receptor is recognized as a well-accepted receptor target for the treatment of obesity, psychiatric, and other disorders.
A novel synthesis of antiobesity drug lorcaserin hydrochloride was accomplished in six steps. N-protection of 2-ethanamine with di-tert-butyl dicarbonate, N-alkylation with allyl bromide, deprotection, intramolecular Friedel-Crafts alkylation, chiral resolution with l-(+)-tartaric acid, and the final salification led to the target molecule lorcaserin hydrochloride in 23.1% overall yield with 99.9% purity and excellent enantioselectivity. This convenient and economical procedure is remarkably applicable for scale-up production
Lorcaserin is an orally administered medication that promotes weight loss. It is used with diet and exercise in overweight adults with a weight-related medical problem or obese adults to lose weight and keep it off. Lorcaserin is a serotonin 2C receptor agonist. Although the exact mechanism of action is not known, lorcaserin is thought to selectively stimulate 5-HT2C receptors in the hypothalamus, the area of the brain known to play a major role in regulating hunger and food intake. By activating these receptors, lorcaserin may decrease food consumption by decreasing appetite and making a person feel full even after eating less food than usual
COA
| Items | Standard | Results |
| Description | White to kind of white powder | kind of white powder |
| Melting point | 193.0-200 | 196.0-198.9 |
| Water | 5-6.5% | 5.6% |
| Solubility | Soluble in methanol | Complies |
| PH | 4.0-6.0 | 5 |
| Heavy Metals | <10ppm | Complies |
| Assay | >96% | 96.21% |
| Residue on ignition | <0.1% | 0.03% |
| Single impurity | <0.2% | 0.19% |
| Conclusion | Up to the Standard USP 32. | |
Use
The U.S. Food and Drug Administration approved Belviq (lorcaserin hydrochloride), as an addition to a reduced-calorie diet and exercise, for chronic weight management.
lorcaserin(Belviq) works by activating the serotonin 2C receptor in the brain. Activation of this receptor may help a person eat less and feel full after eating smaller amounts of food.
Packaging & Delivery
1. Professional team for package and shipment.Special way to ship 100grams to 100kg powders at one time to your country.
2. Fast and discreet shipment could be arranged for customs pass Guaranteed.
3. Tracking code 24 hours for customs pass guaranteed.
4. Many kinds of shipment, also can be as your requirement.
Our Advantage
1. Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2. We have a more profound professional knowledge, you can do a full range of services.
3. Great quality, favorable price and safe transport.
4. Secure and discreet shipment.
5. Parcel can be sent out in 24 hours after payment, express delivery with DHL, EMS, HKEMS, TNT, UPS, Fedex and 24h after-sales service.
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| Polysorbate 80 | ||
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| SARMs | GW501516 | YK11 |
| MK-677/Ibutamoren/Nutrobal |
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