|Place of Origin:||China|
|Certification:||ISO 9001 ,USP,GMP|
|Minimum Order Quantity:||10grams|
|Packaging Details:||Disguised pacakge ; Foil bag|
|Delivery Time:||3-5 work days|
|Payment Terms:||T/T, Western Union, MoneyGram, Bitcoin|
|Supply Ability:||Mass in stock|
|Product Namr:||L-Thyroxine Sodium Salt||Other Name:||T4|
|EINECS:||200-221-4||Melting Point:||207 °C|
|Storage Temp.:||Store At 0-5°C||Water Solubility:||0.15 G/L (25 ºC)|
|Alpha:||16 º (c=2,1M HCl/alcohol 1/4)||Grade:||Pharmaceutical Grade|
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Weight Loss Steroids T4 L-Thyroxine Sodium Salt For Muscle Growth
L-Thyroxine Sodium Salt
Synonyms: SODIUM LEVOTHYROXINE;SODIUM LEVOTHYROXINE, HYDRATE;sodium (2s)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoate;3-[4-4-HYDROXY-3,5-DIIODOPHENOXY-3,5-DIIODOPHENYL]-L-ALANINE, HYDRATE;L-THYROXINE SODIUM SALT;L-THYROXINE SODIUM SALT, HYDRATE;L-THYROXINE SODIUM, HYDRATE;
Product Categories: Hormone Drugs
Appearance: White crystals ,crystalline powder
Water-insoluble substance: 0.1% max
Fumaric Acid: 1.0% max
Maleic Acid: 0.05% max
Heavy metals(as Pb): 10 ppm max
Arsenic(As) : 4 ppm max
Levothyroxine (INN, USAN) or L-Thyroxine Sodium Salt is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated cholesterol levels) but was withdrawn due to cardiac side effects. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
L-Thyroxine Sodium Salt is typically used to treat hypothyroidism, and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy. It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing. Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.
Levothyroxine is typically used to treat hypothyroidism,and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy.It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.
|Appearance||An odorless, almost white or buff colored powder||pass|
|Solubility||1,Very slightly soluble in water||pass|
|2,slightly soluble in alcohol||pass|
|3,practically insoluble in most other organic solvents||pass|
|4,dissolves in diluted aqueous sodium hydroxide solutions||Pass|
|Identification||a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved.||pass|
|b)The retention time of the major peak is confirm to the RS||pass|
|Loss on Drying||Not more than 4.0%||0.46%|
|[a]20/D C=1 in 1M HCL /ETOH 1:4||+18 ~ +22||+20.9o|
|Assay(HPLC)||Not less than 95.0%||99.70%|
|Levothyroxine sodium||Not more than 5.0%||0.68%|
|Conclusion:||Up to the Standard for Export|
One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH).
Levothyroxine is a synthetic (man-made) version of the principle thyroid hormone, thyroxine (T4) that is made and released by the thyroid gland. Thyroid hormone increases the metabolic rate of cells of all tissues in the body. In the fetus and newborn, thyroid hormone is important for the growth and development of all tissues including bones and the brain. In adults, thyroid hormone helps to maintain brain function, food metabolism, and body temperature, among other effects.
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