Sex Steroid Hormones Sildenafil Citrate Vigra For Male Erectile Dysfunction Treatment

Sex Steroid Hormones Sildenafil citrate Vigra For Male Erectile Dysfunction Treatment CAS 171599-83-0

Basic Info.

Model NO.: 171599-83-0

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CAS: 171599-83-0

Assay: 99% Min.

Molecular Weight: 389.4

Chemical Formula: C22H19N3O4

Used: Raw Material Powder

Export Markets: Global

Packing: According to Every Customers′s Requirements

Standard: SGS

Origin: China

HS Code: 2519100000

Production Capacity: 5000kg/Month

COA

Description

Sildenafil citrate is the raw material of , treats erectile dys function and works by relaxing muscles and increases blood flow to particular areas of the body (in this case, the penis, specifically). Its effects last up to four hours. The most common side effects of are headache, facial flushing, and upset stomach. Rarely, blurred vision, or sensitivity to light may briefly occur.

As well as treating impotence, Sildenafil Citrate can also be effective in treating Pulmonary Arterial Hypertension (PAH). Similarly to how it acts to relax muscles of the penis, it relaxes arterial walls; therefore, reducing resistance and pressure in the arteries.

Sildenafil Citrate is solely active in relaxing muscles and increasing blood flow to the heart, lungs and penis due to PDE-5, yet vasodilation is not increased in other parts of the body.

Technical Data: In studies where was administered to over 3700 patients, 19-87 years old in world wide clinical trials. More than 550 patients received treatment post 1 year. 2.5% of the subjects and 2.3% of the placebo subjects reported adverse effects, which were all considered mild. These reported side effects included abnormal or blurred vision and increased sensitivity to light.

All other negative reactions reported, including URI, flu symptoms, back pain and arthralgia, occurred at a rate of less than 2% and equally common in the placebo and administered groups. Effects worsened and were reported more frequently as dosages increased.

Other studies measured duration of sexually stimulated erection using a Rigiscan device. Duration of rigidity was increased by 60% with use.

Application

Sildenafil citrate, sold as , Revatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). It was originally discovered by Pfizer scientists Andrew Bell, David Brown, and Nicholas Terrett.

The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes.

In clinical trials, the most common adverse effects of sildenafil use included headache, flushing, dyspepsia, nasal congestion and impaired vision, including photophobia and blurred vision.Some sildenafil users have complained of seeing everything tinted blue (cyanopsia).Some complained of blurriness and loss of peripheral vision. In July 2005, the FDA found that sildenafil could lead to vision impairment in rare cases and a number of studies have linked sildenafil use with nonarteritic anterior ischemic optic neuropathy.

Rare but serious adverse effects found through postmarketing surveillance include priapism, severe hypotension, myocardial infarction (heart attack), ventricular arrhythmias, stroke, increased intraocular pressure, and sudden hearing loss. As a result of these postmarketing reports, in October 2007, the FDA announced that the labeling for all PDE5 inhibitors, including sildenafil, required a more prominent warning of the potential risk of sudden hearing loss.

Medical Uses

1) Sexual dysfunction, erectile dysfunction

2) Pulmonary hypertension

3) Antidepressant-associated sexual dysfunction

4) Altitude sickness

5) Pulmonary arterial hypertension (PAH)

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