|Place of Origin:||China|
|Certification:||ISO 9001 ,USP,GMP|
|Minimum Order Quantity:||10grams|
|Packaging Details:||Disguised pacakge ; Foil bag|
|Delivery Time:||3-5 work days|
|Payment Terms:||T/T, Western Union, MoneyGram, Bitcoin|
|Supply Ability:||Mass in stock|
|Product Name:||MK-677||Other Name:||Ibutamoren|
|Grade:||Pharmaceutical Grade||Apprarance:||Pale Yellow Or Off White Powder|
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Muscle Building SARMs Raw Powder Ibutamoren Mk 677 CAS: 159634-47-6
Synonym: MK-677;Ibutamoren;L 163191; L163,191; L-163,191; MK0677; MK0677; MK-0677; MK-677; MK677; MK 677;2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-(phenylmethoxy)propan-2-yl]propanamide mesylate
CAS No.: 159752-10-0
Apprarance: pale yellow or off white powder
Export Markets: Global
Store at Dry Room temperature
MK-677 is an orally administered growth hormone secretagogue originally developed by Reverse Pharmacology. A secretagogue is the term for a substance that chemically signals for the pituitary gland to secrete . In other words, MK-677 could be compared to peptides like GHRP-6 or Ipamorelin, only it doesn't require any injections nor does it have any side effects like GHRP-6. This GHS (Growth Hormone Secretagogue) was developed in an aim to combat such conditions as muscle wasting, obesity and osteoporosis. It was also targeted towards treatment of elderly hip fracture patients, so there are a myriad of studies done on safety.
MK-677 is a GH secretagogue taken orally (no injections needed). A GH secretagogue is simply a substance that signals the pituitary gland in your body to secrete more growth hormone.
MK-677 will not negatively affect your testosterone levels in any capacity at all, so there is literally NO chance of any hormonal suppression. Consequently, you don't need to take an aromatase inhibitor or complete a PCT phase after taking MK-677.
The amazing thing, MK-677 causes over a dozen of these extremely strong GH pulsations over the next 24 hours from a single dose, and they don't need injections at all like ALL other growth hormone releasing peptides require.
Inhibits the signaling of somatostatin receptors;
Slows down the activity of somastostatin in the system;
Improves somatotroph signaling in growth hormone releasing hormones (GHRH);
Amplifies and increases the overall production and release of GHRH.
|Characteristics||White to yellowish-white crystalline powder||conform|
|Melting point||32 ~ 37ºC||33~36ºC|
|Specific optical rotation||+77°~+82°||+79.3°|
|Loss on drying||≤0.5%||0.15%|
|Assay||97 ~ 103%||99.08%|
|Free heptanoic acid||≤0.2 %||0.10%|
|Residual solvents(GC)||Methanol ≤100ppm||Pass|
An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARd agonist. Exhibits selectivity for PPARd compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.
In a study on it's effects on catabolic states, a once daily oral dose of 25mgs was given to healthy young men subjected to short-term diet-induced nitrogen wasting. After 7 days of this dose, the subjects showed a sustained increase in serum concentration of I GF-1 and Hormone; in addition, the nitrogen wasting was reversed, showing great potential for treatment of conditions involving muscle wasting.
Trials testing the effects of this GHS on fighting obesity showed an increase in lean body mass, but neither total, nor visceral adipose tissue was effected. This study gave subjects 25mgs of Nutrobal per day for 8 weeks. The subjects showed an increase in basal metabolic rate after 2 weeks, and an increase in serum levels of GH, I GF-1 and I GF-1 binding protein-3. Increase in lean body mass was hypothesized to be caused by an increase in calorie deposition into the muscle and appetite decrease as opposed to reducing fat storage directly.
A study done for the treatment of osteoporosis and bone mineral density showed some increase in bone density, so there is a true impact on bone mineral density. This can help with injury recovery during your cycle.
Other possible benefits of Nutrobal are associated with improved sleep, improved complexion, increase in energy levels, increase nitrogen retention, increase strength and an improved sense of well being. In addition, some studies also suggest that an increased immune system response was caused by Nutrobal (Mk-677), meaning it boosts the immune system to a degree.
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