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Pregnenolone Pharmaceutical Estrogen Female Steroids Hormone Progesterone

Pregnenolone Pharmaceutical Estrogen Female Steroids Hormone Progesterone

  • Pregnenolone Pharmaceutical Estrogen Female Steroids Hormone Progesterone
  • Pregnenolone Pharmaceutical Estrogen Female Steroids Hormone Progesterone
Pregnenolone Pharmaceutical Estrogen Female Steroids Hormone Progesterone
Product Details:
Place of Origin: China
Brand Name: Pharmlab
Certification: ISO 9001, USP,GMP
Model Number: 145-13-1
Payment & Shipping Terms:
Minimum Order Quantity: negotiation
Price: negotiation
Packaging Details: Disguised package ; Foil bag
Delivery Time: 3-5 work days
Payment Terms: Western Union, MoneyGram, T/T, bitcoin
Supply Ability: Mass in stock
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Detailed Product Description
Name: Pregnenolone Other Name: Delta5-Pregnen-3beta-Ol-20-One
Grade: Pharmaceutical Package: Well Disguised Package ;Foil Bag
Purity: 99% Appearance: White Powder
High Light:

active pharmaceutical ingredients

,

pharmaceutical anabolic steroids

Pregnenolone Pharmaceutical Estrogen Female Steroids Hormone Progesterone

 

What is Pregnenolone?

 

Pregnenolone is the parent of all hormones. All other sex hormones are derived from it, including DHEA. It is the super hormone of our brain. The brain and the adrenal cortex produce it and levels decrease as we age. By age 75 we produce only about 40% of our youthful levels.

 

Pregnenolone or "preg" is the most potent memory enhancer ever discovered. Preg enhances our mental performance, facilitates learning, helps us adapt to stress, increases our feeling of well being and actually makes us happier and more appreciative of life. Preg improves concentration, increases productivity and improves psychomotor performance. Preg simply keeps our brain functioning at peak capacity.

 

It is strongly recommended that long-term pregnenolone supplementation be guided by testing levels at least once per year or, better yet, every 6 months. SupplementSpot provides simple and inexpensive saliva tests for this purpose.

 

Quick Details

 

Product Name

Pregnenolone

Synonyms

Delta5-Pregnen-3beta-Ol-20-One;Delta5-Pregnen-3b-Ol-20-One;Delta-5-Pregnene-3b-Ol-20-One;Delta5-Pregnenolone;1-((3s,8s,9s,10r,13s,14s,17s)-3-Hydroxy-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1h-Cyclopenta[a]Phenanthren-17-Yl)-Ethanone;3beta-Hydroxy-5-Pregnen-20-One;3beta-Hydroxypregn-5-En-20-One;3b-Hydroxy-5-Pregnen-20-One

CAS

145-13-1 Steroid Hormone Powder Pregnenolone with Good Effects 145-13-1

MF

C21H32O2

MW

316.48

EINECS

205-647-4

Melting point

188-190 °C

Chemical Properties

White to off-white powder

Usage

Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA an tagonist and increases neurogenesis in the hippocampus. It is a modulator of cytochrome P 450-3A

Definition

ChEBI: A 20-oxo steroid that is pregn-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 20.

 

Description

 

Pregnenolone (3β-hydroxypregn-5-en-20-one), also known as P5, is an endogenous steroid hormone. It is the precursor of the progestogens, mineralocorticoids, glucocorticoids, androgens, and estrogens, as well as the neuroactive steroids. In addition, pregnenolone is biologically active in its own right, acting as a neurosteroid.

 

Like other steroids, pregnenolone consists of four interconnected cyclic hydrocarbons. It contains ketone and hydroxyl functional groups, two methyl branches, and a double bond at C5, in the B cyclic hydrocarbon ring. Like many steroid hormones, it is hydrophobic. Its esterified version, pregnenolone sulfate, is water-soluble.

 

Pregnenolone undergoes further steroid metabolism in one of three ways.


Pregnenolone can be converted to progesterone. The critical enzyme step is two-fold using a 3-beta-hydroxysteroid dehydrogenase and a delta 4-5 isomerase. The latter transfers the double bond from C5 to C4 on the A ring. Progesterone is the entry into the delta-4-pathway, resulting in production of 17-hydroxy progesterone and andros tenedione, precursor to test osterone and estrone. Aldosterone and corticosteroids are also derived from progesterone or its derivatives.


Pregnenolone can be converted to 17-hydroxy-pregnenolone by the enzyme 17α-hydroxylase (CYP17A1). Using this pathway, termed delta-5 pathway, the next step is conversion to dehydroepiandros terone (DH EA) using a desmolase. DH EA is the precursor of andros tenedione.


Pregnenolone can be converted to androsta-5,16-dien-3 beta-ol by 16-ene synthetase.

 

Application

 

Pregnenolone is used for fatigue and increasing energy; Alzheimer's disease and enhancing memory; trauma and injuries; as well as stress and improving immunity.


It is also is used for skin disorders including psoriasis and scleroderma.


Women use pregnenolone for lumpy breasts (fibrocystic breast disease), a disorder of the lining of the uterus (endometriosis), symptoms of menopause, andpremenstrual syndrome (PMS).


Some people use pregnenolone for slowing or reversing aging, arthritis, anddepression. It is also used for strengthening the heart, allergic reactions, "detoxification," lupus, multiple sclerosis (MS), prostate problems, and seizures.

 

COA

 


TEST ITEMS


SPECIFICATION


RESULTS


Description


White or Almost White Crystalline Powder


white powder


Identification


A.B.


Positive


Assay


97.0~103.0%


99.3%


Specific Rotation


+101°~+105°


+102.6°


Loss On Drying


1.0%max


0.27%


Melting Point


153~157°C


153.0~155.0°C


Organic Volatile Impurities


meets the requirement.


Conforms


Related Substances


meets the requirement.


Conforms


Residual Solvents


meets the requirement.


Conforms


Particle Size


100% ≤ 20 microns


Conforms


Conclusion


The specification conform with USP30 standard

 

Competitive Advantage

 

1. Our company is a professional production leading factory in China in pharmaceutical area of many years.

 

Delivery areas of our products: US, UK, Canada, Australia, Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on.

 

Payment method: T/T, Western union, Moneygram, bitcoin etc.

 

2. Discreet package. The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration.

 

3. Top quality. High quality guarenteed, once any problem is found, the package would be reshipped for you.

 

4. Security Shipping: Shipping by express (FedEx, UPS, DHL, EMS), by air. The most professional forwarder would be recommanded for you.

 

5. We have stock, so we can delivery quickly at the very day when receive the payment.

 

6. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.

 

7. A discount would be given when you make a large order.

 

Pregnenolone

 

Pregnenolone Pharmaceutical Estrogen Female Steroids Hormone Progesterone 1

 

Pregnenolone Pharmaceutical Estrogen Female Steroids Hormone Progesterone 2

 

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