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Natural Anti Estrogen Steroids Tamoxifen citrate Anabolic Steroid Articles for Cancer Treatment

Natural Anti Estrogen Steroids Tamoxifen citrate Anabolic Steroid Articles for Cancer Treatment

  • Natural Anti Estrogen Steroids Tamoxifen citrate Anabolic Steroid Articles for Cancer Treatment
  • Natural Anti Estrogen Steroids Tamoxifen citrate Anabolic Steroid Articles for Cancer Treatment
  • Natural Anti Estrogen Steroids Tamoxifen citrate Anabolic Steroid Articles for Cancer Treatment
Natural Anti Estrogen Steroids Tamoxifen citrate Anabolic Steroid Articles for Cancer Treatment
Product Details:
Place of Origin: China
Brand Name: Pharmlab
Certification: ISO 9001, USP,GMP
Model Number: 54965-24-1
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: negotiable
Packaging Details: Well disguised package ; Plastic drum with safe shipping
Delivery Time: 3~7 work days
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: Mass in stock
Contact Now
Detailed Product Description
Product Name: Tamoxifen Citrate Usage: Cancer Treatment
Appearance: White Powder Grade: Pharmaceutical Grade
MF: C32H37NO8 MW: 563.64
Shiping: EMS,HKEMS,FEDEX,DHL,TNT,Aramex,etc Package: Foil Bag; Well Disguised Package
Shipping Policy: 100% Free Resend Shipping
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Anti - Estrogen Anabolic Steroid White Powder Tamoxifen Citrate Nolvadex CAS 10540-29-1

 

Quick details:
Product Name: Tamoxifen citrate
Other name:  Nolvadex
CAS:  54965-24-1
MF:  C32H37NO8
MW:  563.64
EINECS:  259-415-2
Appearance: white to off-white powder
Grade: medical garde
Assay: 99%
Usage: 
 For the treatment of advanced and recurrent breast cancer and ovarian cancer, etc.
estrogen antagonist, antineoplastic, anti-estrogen, protein kinase C inhibitor, beneficial cardiovascular effects, bone cancer treatment, induces DNA adduct formation
Storage: Sealed in the 2 ºC -8 ºC
Melting point:140-144 °C
Boiling point:665.9ºC at 760 mmHg
flash point: 356.5ºC

 

 

Description:

 

Tamoxifen citrate(tamoxifen, abbreviated TCT) is an estrogen competitive antagonist and a nonsteroidal anti estrogen drug. It can compete with estrogen (estradiol), estrogen receptor in breast cancer cells, inhibit the action of estrogen on cancer cells, inhibit the growth and development of tumor cells, and show the anti-cancer effect.

 

Clinically, tamoxifen citrate is commonly used for the treatment of various types of breast cancer, especially with estrogen receptor and progesterone receptor positive and has low prostate-specific antigen levels in postmenopausal women with breast cancer.


Nolvadex (tamoxifen citrate) is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure. It is not correct that Nolvadex reduces levels of estrogen: Rather, it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do nothing.


The claim that Nolvadex reduces gains should not be taken too seriously. The fact is that any number of bodybuilders have made excellent gains while using Nolvadex.


The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction (individuals using anabolic steroids were not studied though) from use of Nolvadex.

 

Natural Anti Estrogen Steroids Tamoxifen citrate Anabolic Steroid Articles for Cancer Treatment 0

 

Applications:


Nolvadex is the trade name for the drug tamoxifen citrate, it is a non-steroidal agent that demonstrates potent anti-estrogenic properties. The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. With the tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an anti-estrogenic effect is achieved.

 

Since many forms of breast cancer are responsive to estrogen, the ability of tamoxifen citrate to block its action in such cells has proven to be a very effective treatment. It is also utilized successfully as a preventative measure, taken by people with an extremely high familial tendency for breast cancer. While Nolvadex is effective against estrogen, it is not our strongest available remedy.


Nolvadex is an estrogen agonist in the liver, capable of activating the estrogen receptor and mimicking the actions of this sex hormone in this region of the body. As such it can have a markedly positive impact on HDL (good) cholesterol values, as does estrogen.

 

 

Functions:


Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist. Tamoxifen is the usual endocrine (anti-estrogen) therapy forhormonereceptor-positivebreast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting.

 

Tamoxifen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, tamoxifen acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. Hence breast cancer cell growth is blocked.


The goods to anti-estrogen fertility inducer, the objects in dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecologic diseases; It is used as a first line defense against breast cancer. Nolvadex or Tamoxifen citrate, a non-steroidal antiestrogen for oral administration, is commonly by athletes as a post cycle therapy drug to reduce or prevent the formation of excess estrogens that can lead to oily skin, acne, fluid retention, and gynecomastia.
 

 

Dosage:


The oral absorption of TCT is slow and plasma concentrations get peaked within 3 to 6 hours. After absorbed in the liver, Tamoxifen citrate is metabolized into N-demethyl tamoxifen whose activity is similar to Tamoxifen citrate. Tamoxifen citrate has a half-life of 5 ~ 7 days, its metabolite N- demethylation has 7 ~ 14 days.


For a single oral dose of TCT 20mg, its plasma concentration peak was about 40ng / ml (range 67 to 183ng / ml) and 336ng ml (range: 148 to 654ng / ml).


Steady state plasma concentration requires continuous application of tamoxifen citrate for 3 to 4 weeks, and it also requires continuous administration of N- methyl 3 to 8 weeks. Tamoxifen citrate, like most other metabolites are excreted mainly in faeces, and small amounts of metabolites excreted in urine.

 

 

COA

Test Specification Results
Identification

UV spectrum

IR spectrum

Positive

Positive

Characteristics White to almost white crystalline powder conform
Melting point 220 ~ 230℃ 221~226℃
Specific optical rotation ﹢112°~﹢120° '+114°
Residue on ignition ≤0.2% 0.05%
Solubility practically insoluble in water,freely soluble in chloroform ,slight soluble alcohol and vegetable oil Pass
Heavy metal ≤0.001% 0.0006%
Residual solvents(GC)

Methylene chloride ≤ 600ppm

Methanol ≤3000ppm

Pyridine≤200ppm

Acetone≤5000ppm

Pass

Pass

Pass

Pass

Loss on drying ≤0.5% 0.21%
Assay 99.0 ~ 101.0% 99.55%
Particle size 100%≤20um Pass
Conclusion This batch complies with Enterprise Standard

 

Natural Anti Estrogen Steroids Tamoxifen citrate Anabolic Steroid Articles for Cancer Treatment 1


Tips:

 

HOW TO MAKE AN ORDER?

 

1. Tell us what you need ( use for what/product name & quantity ), you will get an advice and a quotation.


2. Full payment would be done once we come to an agreement on all details .


3. Your goods will be sent out within 24 hours after payment , tracking number available.


4. The goods will reach you in 3~7 days.


WHY CHOOSE US?

1. High quality: Our factories are professional in raw powder production with experience over 10 years. Having good reputation all over the world, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.

 

2. Competetive price: All powders are factory directly supplied, it's factory price and negotiable.

 

3. Fast and safe delivery: Your goods will be sent out within 24 hours after payment, tracking number available, customs pass rate ≥99%.

 

4. Good pre&after-sales service: Any problem please feel free to contact us, we will always be online for you.

 

High quality, competetive price, fast and safe delivery, good service,that's us! Welcome to contact!

 

 

 

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