|Place of Origin:||China|
|Certification:||ISO 9001, USP,GMP|
|Minimum Order Quantity:||1kg|
|Packaging Details:||Well disguised package ; Bottled with safe shipping|
|Delivery Time:||3~5 work days|
|Payment Terms:||Western Union, MoneyGram, T/T, Bitcoin|
|Supply Ability:||Mass in stock|
|Product Name:||Gamma-Hydroxybutyrate||Alias:||GBL; GHB|
|Grade:||Pharm Grade||Usage:||Used For Mind-blower|
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Gamma-butyrolactone is one kind of important fine chemicalintermediate, simultaneously also is one kind of performance fine highboiling point solvent, ideal antioxidant, plasticizer,extracting agent, absorbent, dispersing agent, solid stain, Coagulation Reagent.
Product Name: gamma-Butyrolactone; GBL
Chemical Properties: Clear colorless oily liquid with a pleasant odor
Category: Flammable substance
Specification : Magic GBL with Magic effect
Usage: Gamma-butyrolactone is one kind of important fine chemicalintermediate, simultaneously also is one kind of performance fine highboiling point solvent, ideal antioxidant, plasticizer,extracting agent, absorbent, dispersing agent, solid stain, Coagulation Reagent.
Melting point: −45 °C
Boiling point: 204-205 °C
Density: 1.12 g/mL at 25 °C
Water Solubility: MISCIBLE
Stability: Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong acids, strong bases, strong reducing agents
Acute toxicity: Oral-rat LD50: 1540 mg/kg; oral-mouse LD50: 1720 mg/kg
Storage and transportation properties: Make sure ventilating, low temperature and drying in the warehouse; separate from the oxidant; prevent fires.
GBL is a hygroscopic colorless liquid with a weak characteristic odor which is soluble in water. GBL is a common solvent and reagent in chemistry as well as being used as a flavouring, as a cleaning solvent, as a superglue remover, and as a solvent in some wet aluminium electrolytic capacitors. In humans it acts as a prodrug for GHB, and it is used as a recreational intoxicant with effects similar to alcohol.
GBL is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non-nucleophilic base, like lithium diisopropylamide, GBL can become an alpha-carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.
GBL is rapidly converted into GHB by paraoxonase (lactonase) enzymes, found in the blood. Animals which lack these enzymes exhibit no effect from GBL. GBL is more lipophilic (fat soluble) than GHB, and so is absorbed faster and has higher bioavailability. Because of these pharmacokinetic differences, GBL tends to be more potent and faster-acting than GHB, but has a shorter duration; whereas the related compound 1,4-butanediol (1,4-B) tends to be slightly less potent, slower to take effect but longer-acting than GHB.
Maleic anhydride hydrogenation method is an advanced technology developed in 1970s. It can produce tetrahydrofuran and γ-butyrolactone in any proportion with a hydrogenation reaction, and the usual ratio is tetrachlorofuran: γ-butyrolactone = 3-4:1.
There are many production enterprises, but usually in small scale. The average level is 300t/a. The production capacity account for 30% of the total domestic production capacity. 2.1, 4-butanediol dehydrogenation reactor is a tube array reactor, filled with flake copper catalyst (with zinc oxide as the carrier). The reaction temperature is controlled at 230-240 ° C. The yield of the product is obtained by reduced pressure distillation of and the yield is above 77%.
1. Can be hydrolyzed to produce γ-hydroxy butyric acid, can be used as a special plasticizer plastic, pharmaceutical intermediates;
2. Can be oxidized to produce succinic acid; reduced to 4-hydroxy butyraldehyde, and then reduced to 1,4-butanediol;
3. Can be condensed to produce α, α - dihydroxy ketone acetal;
4. Can react with CH3NH2 to form N-methyl-2-pyrrolidone;
5. Can generate tetrahydrofuran;
6. Can react with SO3 to form butyrolactone-α-sulfonic acid;
7. Can react with NaCN to form 2-piperidone;
8. Can react with CO to produce glutaric acid;
9. Can react with NaOH to produce 4,4 - oxo succinic acid;
10. Can react with Na2S to form thiolated succinic acid;
With NA2SO3 reaction to generate sodium γ-sulfobutyrate.
Pharmlab is a professional supplier in China ,we had specilized in this field over for 10 years .Exporting pharmaceutical intermediates ,anabolic steroids ,peptide and sarms raws Injectable steroids oil also could be provided in our lab . The price for 1L GBL just 70USD (100USD shipping included for a trial order) .
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Tags: GBL, GHB, Gamma-Hydroxybutyrate
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