|Place of Origin:||China|
|Certification:||ISO 9001, USP, GMP|
|Minimum Order Quantity:||10g|
|Packaging Details:||Well disguised package with safe new shipping method;As requested.|
|Delivery Time:||Shipment within 24 hours, 3 to 5 days arrived|
|Payment Terms:||Western Union, Money Gram, T/T, Bitcoin|
|Supply Ability:||Mass In Stock|
|Appearence:||White Or Almost White Fine Crystalline Powder||Grade:||Pharmaceutical Grade|
|MW:||416.57||Shipping Method:||EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC|
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English name: Spironolactone
EINECS Number: 200-133-6
Density: 1.24 g/cm3
Melting Point: 207-208 °C(lit.)
Boiling Point: 597 °C at 760 mmHg
Flash Point: 302.3 °C
Solubility: practically insoluble in water
Appearance: White or almost white fine crystalline powder
What Is Spironolactone?
Spironolactone, marketed beneath the brand name Aldactone amongst others, is a medication which is primarily accustomed to treat fluid build-up because of heart failure, liver scarring, or kidney disease. Additionally it is used in the treating high blood pressure, low blood potassium that will not improve with supplementation, early-onset puberty, and acne and excessive growth of hair in women. It is also used for hormone therapy in transgender women. Spironolactone is taken orally.
Spironolactone commonly referred to simply as spiro, and marketed primarily within the brand name Aldactone for most countries, is often a synthetic, steroidal antimineralocorticoid and antiandrogen that also has some weak progestogen properties, and also some indirect estrogen and glucocorticoid effects. It really is used primarily being a diuretic and antihypertensive, but can also be employed for the goal of reducing elevated or unwanted androgen activity within the body. It acts predominantly being an antagonist with the mineralocorticoid and androgen receptors, plus relation to its antimineralocorticoid effects, is assigned to a class of drugs known as potassium-sparing diuretics.
Spironolactone can be used primarily to help remedy heart failure, edematous conditions like nephrotic syndrome or ascites in patients with liver disease, essential hypertension, hypokalemia, secondary hyperaldosteronism, and Conn's syndrome .
Spironolactone Medical Uses
Spironolactone is utilized primarily to help remedy heart failure, edematous conditions such as nephrotic syndrome or ascites in people with liver disease, essential hypertension, hypokalemia, secondary hyperaldosteronism (including occurs with hepatic cirrhosis), and Conn's syndrome (primary hyperaldosteronism). Alone, spironolactone is only a weak diuretic since it primarily targets the distal nephron (collecting tubule), where only small quantities of sodium are reabsorbed, but it can be combined with other diuretics to boost efficacy.
Spironolactone comes as 25 milligrams (mg), 50 mg, and 100 mg oral tablets.
Dosage depends on your health issue:
Primary hyperaldosteronism: 100 to 400 mg daily
Edema: 25 to 200 milligrams every day, for at least 5 days
Essential hypertension: 50 to 100 mg every day, for at least two weeks
Hypokalemia: 25 to 100 mg once daily
Severe heart failure: 25 mg once daily, which may be increased to 50 mg once daily or decreased to 25 mg once every other day, depending on your tolerance of the drug
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