|Place of Origin:||China|
|Certification:||ISO 9001, USP,GMP|
|Minimum Order Quantity:||10g|
|Packaging Details:||Disguised package ; Foil bag|
|Delivery Time:||3-5 work days|
|Payment Terms:||Western Union, MoneyGram, T/T, bitcoin|
|Supply Ability:||Mass in stock|
|Product Name:||Articaine Hydrochloride||Other Name:||Articaine HCL|
|Shipping Time:||3-5 Work Days||Package:||Disguised Package|
topical anesthetic drugs,
pain killer drugs
Local Anesthetic Drugs Articaine hydrochloride For Pain Control CAS 23964-57-0
|Product Name||Articaine Hydrochloride|
|Synonyms||methyl 4-methyl-3-[[(1-oxo-2-(propylamino)propyl]amino]-2-thenoate monohydrochloride; Carticaine HCl; Ultracaine; CARTICAINE HYDROCHLORIDE; Ultracain;Articaine hydrochloride; Methyl 4-methyl-3-(2-propylaminopropanoylamino)thiophene-2-carboxylate hydrochloride; 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylic acid methyl ester hydrochloride|
|Categories||Local anesthetic; Pharmaceutical intermediate|
Articaine Hydrochloride,Articaine is an intermediate-potency, short-acting amide local anesthetic with a fast metabolism due to an ester group in its structure. It is effective with local infiltration or peripheral nerve block in dentistry, when administered as a spinal, epidural, ocular, or regional nerve block, or when injected intravenously for regional anesthesia.
Articaine Hydrochloride,In comparative trials, its clinical effects were not generally significantly different from those of other short-acting local anesthetics like lidocaine, prilocaine, and chloroprocaine, and there is no conclusive evidence demonstrating above-average neurotoxicity. Articaine proved to be suitable and safe for procedures requiring a short duration of action in which a fast onset of anesthesia is desired, eg, dental procedures and ambulatory spinal anesthesia, in normal and in special populations.
How ot works ?
Articaine Hydrochloride,Articaine blocks nerve conduction by reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, similar to other local anesthetics. Binding of articaine to the sodium channel reduces sodium influx so that the threshold potential will not be reached and impulse conduction stops. The blocking action of articaine on the sodium channel is state dependent: it has the highest affinity for the open state, an intermediate affinity for the inactivated state, and the lowest affinity for the resting state.
Articaine Hydrochloride,The degree of neuronal block is affected by the diameter of the nerve. Larger-diameter fibers (touch/pressure/ motor) require higher concentrations of local anesthetic compared with small myelinated fibers (pain afferents).Articaine is lipid soluble, highly protein-bound (94%), and has a dissociation constant (pKa) of 7.8. Articaine is an intermediate-potency, short-acting local anesthetic with a fast onset of action.
Characteristic for Articaine HCl is that they are fast acting and effective in penetrating bone. The latter has not been proven scientifically but is the opinion of those who work with these products. When using articaine HCl, the patient no longer has to return to the waiting room to allow the anesthetic to take effect. During treatment, it seems as though articaine HCl are more effective than most other anesthetics. For these reasons, increasing numbers of dentists and dental surgeons are opting for articaine HCl.
We do understand that you will be worried about our packing methods before you tried or knew us, while we are making the real deal and we do know how customs works.
We have professionfal team for special disguised package, no word concern steroid will be whown on the parcels, the pass custom rate is more than 99%.
Before we could be able to offer some details of our package and shipping methods, and it is better to discuss by mail , skype or whatsapp.
Our company owns a professional and efficient team for packing with our best discrete or stealth packages. Orders will be sent out within only one working day after payment.Package details and tracking number will be ent to you.Shipment by DHL, TNT, FedEx, HKEMS, UPS, ,EUB,ETK and so on.
It usually takes 4 to 7 days or 7 to 10 days by some other express courier; it will be 15 to 20 days by slowpost.
Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
We will stack on the parcels until you get them on hand so that you do not need to spare time on this.
1. We focus on pharmaceutical raw materials and their steroid powders for more than 10 years, with a wealth of experience in this field.
2. Over 90% of powders are exported to North America, European, Southeast Asia, Africa and South America, and are welcomed and trusted by the customer with our excellent product and competitive price.
3. Package: We have professional team to pack your items with professional materials, it is 100% safe.
4. Delivery: Most powders we have mass stock, package can be send within 24hours after your order, of course, will tell you the packing details and tracking details asap. Usually it takes about 3-6 business days from China to your doorstep.
5. Service: We will always send you top quality products with very competitive price.
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