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Articaine Hydrochloride for Anti-Paining Anesthetic Articaine HCL CAS 23964-57-0

Articaine Hydrochloride for Anti-Paining Anesthetic Articaine HCL CAS 23964-57-0

  • Articaine Hydrochloride for Anti-Paining Anesthetic Articaine HCL CAS 23964-57-0
  • Articaine Hydrochloride for Anti-Paining Anesthetic Articaine HCL CAS 23964-57-0
Articaine Hydrochloride for Anti-Paining Anesthetic Articaine HCL CAS 23964-57-0
Product Details:
Place of Origin: China
Brand Name: Pharmlab
Certification: ISO 9001, USP,GMP
Model Number: 23964-57-0
Payment & Shipping Terms:
Minimum Order Quantity: negotiation
Price: negotiation
Packaging Details: Disguised package ; Foil bag
Delivery Time: 3-5 work days
Payment Terms: Western Union, MoneyGram, T/T, bitcoin
Supply Ability: Mass in stock
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Detailed Product Description
Product Name: Aarticaine Hydrochloride CAS: 23964-57-0
Other Name: Carticaine Hydrochloride Appearance: White Crystalline Powder
Shipping Policy: Sample Order Available Shipping Methods: EMS,HKEMS,FEDEX,DHL,TNT,Aramex,ETC
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Articaine Hydrochloride for Anti-Paining Anesthetic Articaine HCL CAS 23964-57-0

 

Quick Details

 


Product Name
Aarticaine hydrochloride
Synonyms Articaine hydrochloride [USAN]; 2-Thiophenecarboxylic acid, 4-methyl-3-((1-oxo-2-
(propylamino)propyl)amino)-, methyl ester, monohydrochloride; 4-Methyl-3-(2-
(propylamino)propionamido)-2-thiophenecarboxylic acid methyl ester HCl; Articaine HCl; Articaine hydrochloride;
Carticaine hydrochloride; HOE 045; HOE 40045; Methyl 4-methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylate, monohydrochloride; Septanest; Septocaine; UNII-QS9014Q792; Ultracain; Ultracaine; 2-Thiophenecarboxylic acid, 4-methyl-3-(2-(propylamino)propionamido)-, methyl ester, monohydrochloride; Methyl 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-2-thenoate monohydrochloride; methyl 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylate hydrochloride (1:1)
Molecular Formula C 13 H 21 ClN 2 O 3 S
Molecular Weight 320.8354
InChI InChI=1/C13H20N2O3S.ClH/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4;/h7,9,14H,5-6H2,1-4H3,(H,15,16);1H
CAS Registry Number 23964-57-0
EINECS 245-957-7
Boiling point 440.6 C at 760 mmHg
Flash point 220.3 C
Vapour Pressure 5.79E-08mmHg at 25 C
Assay 99%
Appearance White crystalline powder

 

Description


Articaine hydrochloride , its CAS NO. is 23964-57-0, the synonyms are 2-Thiophenecarboxylic acid,

4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, methyl ester, monohydrochloride ; 4-Methyl-3-

(2-(propylamino)propionamido)-2-thiophenecarboxylic acid methyl ester HCl ; Articaine HCl ; Methyl

4-methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylate, monohydrochloride ; Septanest ; Septocaine .


Articaine is a dental local anesthetic. It is the most widely used local anesthetic in a number of European countries and is available in many countries around the world.

 

Structure and metabolism

 

The amide structure of articaine is similar to that of other local anesthetics, but its molecular structure differs through the presence of a thiophene ring instead of a benzene ring. Articaine is exceptional because it contains an additional ester group that is metabolized by esterases in blood and tissue. The elimination of articaine is exponential with a half-life of 20 minutes. Since articaine is hydrolized very quickly in the blood, the risk of systemic intoxication seems to be lower than with other anesthetics, especially if repeated injection is performed.

 

Applications


Articaine is a local anaesthetic that has been approved overseas for several years. Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve. This action is prolonged by combining the drug with a vasoconstrictor such as adrenaline.


The combination of articaine and adrenaline can be used for local or regional anaesthesia for dental procedures. Anaesthesia begins within six minutes and lasts for an hour. The half-life of articaine is approximately 1.8 hours. It is metabolised and then mainly excreted in the urine.

 

Aarticaine HCl Specification

 


Items

Specifications

Results

Description

White or almost white powder

Conforms

Identification

IR& HPLC

Conforms

Specific Rotation

+32°~+36°

+33.26°

Related substances

Impurity D , G≤0.3%

Conforms

Impurity A , B , C , E , F , H , I≤0.2%

Conforms

Impurity with RRT 1.23≤0.2%

Conforms

Any other impurity≤0.1%

Conforms

Total impurity≤1.2%

0.75%

Acetone

≤1.0%

Conforms

Water

≤0.2%

0.12%

Assay (by HPLC)

97.0 ~ 102%

99.05%

Particle size

90%≤10μm

Conforms

Conclusion

The results conform to EP6

 

Articaine Hydrochloride Use

 

Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient and completely reversible state of anesthesia (loss of sensation) during (dental) procedures.

In dentistry, articaine is used both for infiltration and block injections, with the block technique yielding the greatest duration of anesthesia.

 

In people with hypokalemic sensory overstimulation, lidocaine is not very effective, but articaine works well.

 

Aarticaine HCl

 

Articaine Hydrochloride for Anti-Paining Anesthetic Articaine HCL CAS 23964-57-0 0

 

Competitive Advantage

 

1. Our company is a professional production leading factory in China in pharmaceutical area of many years.

 

Delivery areas of our products: US, UK, Canada, Australia, Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on.

 

Payment method: T/T, Western union, Moneygram, bitcoin etc.

 

2. Discreet package. The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration.

 

3. Top quality. High quality guarenteed, once any problem is found, the package would be reshipped for you.

 

4. Security Shipping: Shipping by express (FedEx, UPS, DHL, EMS), by air. The most professional forwarder would be recommanded for you.

 

5. We have stock, so we can delivery quickly at the very day when receive the payment.

 

6. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.

 

7. A discount would be given when you make a large order.

 

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