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129453-61-8 Pharmaceutical Raw Materials Anti Estrogen Steroids Fulvestrant Faslodex For Cutting Cycle

129453-61-8 Pharmaceutical Raw Materials Anti Estrogen Steroids Fulvestrant Faslodex For Cutting Cycle

  • 129453-61-8 Pharmaceutical Raw Materials Anti Estrogen Steroids Fulvestrant Faslodex For Cutting Cycle
  • 129453-61-8 Pharmaceutical Raw Materials Anti Estrogen Steroids Fulvestrant Faslodex For Cutting Cycle
129453-61-8 Pharmaceutical Raw Materials Anti Estrogen Steroids Fulvestrant Faslodex For Cutting Cycle
Product Details:
Place of Origin: China
Brand Name: Pharmlab
Certification: ISO 9001, USP,GMP
Model Number: 129453-61-8
Payment & Shipping Terms:
Minimum Order Quantity: 1g
Price: negotiation
Packaging Details: Well disguised package ; Plastic drum with safe shipping
Delivery Time: 3~5 work days
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: Mass in stock
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Detailed Product Description
Product Name: Fulvestrant Other Name: Faslodex
Melting Point: 104-106°C Storage Temp.: 2-8°C
Usage: Anti-Estrogen Chemical Properties: White Crystalline Powder
High Light:

active pharmaceutical ingredients

,

pharmaceutical anabolic steroids

Anti-Estrogen Steroids Fulvestrant Faslodex For Cutting Cycle 129453-61-8

 

 

Quick Details:

  •  
  • Fulvestrant
  • CAS: 129453-61-8
  • MF: C32H47F5O3S
  • MW: 606.77
  • Usage: Antiestrogen; A novel steroidal estrogen antagonist reported to lack any partial agonist activity. Antineoplastic (hormonal).
  • Purity: 99.56%
  • Appearance: White crystalline powder
  • Min. Order: 1g
  • Package: Super discreet to ensure 100% pass rate
  • Stock: Mass and plenty---Prompt shipment
  • Payment: T/T, Bank Transfer, Western Union, Money Gram and Bitcoin
  • Delivery: All Express Modes (EMS, DHL, TNT, FedEx, UPS, etc.)
  • Shipping time: 5-7 days by express door-to-door


Description:

 

Fulvestrant, sold under the trade name Faslodex among others, is used to treat hormone receptor positive breast cancer (breast cancer that depends on hormones such as estrogen to grow) in women who have experienced menopause (change of life; end of monthly menstrual periods) and whose breast cancer has worsened after they were treated with antiestrogen medications such as tamoxifen (Nolvadex). It works to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women with disease progression as well as HR-positive, HER2-negative advanced breast cancer in combination with palbociclib in women with disease progression after endocrine therapy.

 

It is given by injection into a muscle.

 


Medicine for breast cancer


Fulvestrant (trade name Faslodex) which was developed by AstraZeneca isan intramuscular injection drug, and it was approved for marketing by the US Food and Drug Administration in April 2002.Fulvestrantis a drug treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. The use of hormone therapy to treat cancer is based on the observation that receptors for specific hormones that are needed for cell growth are on the surface of some tumor cells.Many breast cancer cells have estrogen receptor (ER), and these cancers rely on the hormone oestrogen to grow, This type of breast cancer is called oestrogen-receptor positive (ER positive) breast cancer. Drugs that block the effects of these hormones can slow or stop the growth of the breast cancer cells.

 

Fulvestrant stops oestrogen getting to the cancer cells by blocking oestrogen receptors and reducing the number of receptors the cancer cells have.Thus, fulvestrant is a " pure" estrogen receptor antagonists, it has no partial estrogen-like effect of excitement, which can inhibit estrogen signaling pathway by binding, blocking and reduced ER. Fulvestrant has competitively combine with ER, its binding capacity with ER was the same as estrogen, but is about 100 times as tamoxifen.Fulvestrant provided effective second-line therapy in this setting for postmenopausal women whose breast cancer has worsened after they were treated with antiestrogen medications such as tamoxifen.Fulvestrant is a hormone therapyand itdoes not cause common adverse reactions as in chemotherapy, so it has a better patient compliance. A number of clinical studies have approved that a dosage of 250mgfulvestrant has a outstanding effect and security stability in the second-line treatment of advanced breast cancer.

 


Mechanism of action

 

Fulvestrant is a steroid anti-estrogen drugs, its chemical structure is almost like estradiol, the difference is that there is functional group at 7α position, thus it is a analogues of 17β-estradiol alkylamines. Many breast cancer cells have estrogen receptor (ER) which are stimulated to grow by the female sex hormones oestrogen and progesterone. Fulvestrant can stop oestrogen getting to the cancer cells by blocking oestrogen receptors and reducing the number of receptors the cancer cells have.It can antagonize the action of estrogen by occupying the ER, and thereby suppress stimulation of gene activation by estrogen, so as toaffect estrogen related processes required by cell cycle.Its affinity with ER is close to estrogen, which is100 times as tamoxifen. Apoptosis is very essential in maintaining homeostasis, and it could also be another major mechanism offulvestrant therapy.

 129453-61-8 Pharmaceutical Raw Materials Anti Estrogen Steroids Fulvestrant Faslodex For Cutting Cycle 0

 

Fulvestranthas poor oral bioavailability, it comes as a solution (liquid) in the buttockto be administeredvia intramuscular injection once a month.Open, randomized and multi-center study in postmenopausal women with advanced breast cancer showed that dosage ofonce 5 ml or twice 2.5 ml injection of fulvestrant product 250 mg have no significant difference on pharmacokinetic and toxicity,but have individual differences in blood concentration and dose-dependent manner. The serum LH, FSH or SBHG levels did not change significantly during 7d treatment. Fulvestrant can`t pass into blood-brain barrier to cause side effects such as vasomotor.Theoretically, estrogen inactivation can lead to increased bone turnover, promote osteoporosis, however this dosen`t happenedin animal models. Fulvestrant can`t lead to increased surrogate marker of bone turnover.

 


Uses

 

Fulvestrant is used to treat hormone receptor positive breast cancer (breast cancer that depends on hormones such as estrogen to grow) in women who have experienced menopause (change of life; end of monthly menstrual periods) and whose breast cancer has worsened after they were treated with antiestrogen medications such as tamoxifen (Nolvadex). Fulvestrant is in a class of medications called estrogen receptor antagonists.

 

 

Products

 

Testosterone Acetate Trenbolone Acetate MGF
Testosterone Cypionate Trenbolone Enanthate PEG MGF
Testosterone Decanoate Boldenone Acetate CJC-1295
Testosterone Enanthate Boldenone undecylenate CJC-1295 DAC
Testosterone Isocaproate Boldenone Cypionate PT-141
TestosteronePhenylpropionate Boldenone Propionate Melanotan-1
Testosterone Propionate Nandrolone Decanoate Melanotan-2
Testosterone Undecanoate Nandrolone phenylpropionate GHRP-2
Mesterone Nandrolone undecylate GHRP-6
Testosterone Sustanon 250 Nandrolone cypionate Ipamorelin
Clostebol Acetate Nandrolone propionate Hexarelin
Methylandrostanolone Methyltrienolone Sermorelin
Methenolone Enanthate Drostanolone Propionate Oxytocin
Methenolone Acetate Drostanolone Enanthate TB500
Anadrol Stanolone Fragment 176-191
Anavar Tadalafil Triptorelin
Winstrol Vardenafil Tesamorelin
Clomifene citrate Dianabol Gonadorelin
Toremifene citrate Tamoxifen Citrate DSIP
Finasteride hydrochloride Selank

 

Peptides Specification:

 

Name Specification Name Specification
MGF 2mg/vial Hexarelin 2mg/vial
PEG MGF 2mg/vial Sermorelin 2mg/vial
CJC-1295 with DAC 2mg/vial Oxytocin 2mg/vial
CJC-1295 without DAC 2mg/vial TB500 2mg/vial
PT-141 10mg/vial BPC 157 2mg/vial
MT-1(Melanotan) 10mg/vial 176-191 2mg/vial
MT-2 10mg/vial Triptorelin 2mg/vial
GHRP-2 5mg/vial Tesamorelin 2mg/vial
GHRP-2 10mg/vial Gonadorelin 2mg/vial
GHRP-6 5mg/vial Gonadorelin 10mg/vial
GHRP-6 10mg/vial DSIP 2mg/vial
Ipamorelin 2mg/vial Selank 5mg/vial

 

Semi Finished Steroids Solution:

 

Testosterone Enanthate(Primoteston) 250mg/ml / 300mg/ml
Testosterone Propionate 100mg/ml
Testosterone Cypionate 250mg/ml / 300mg/ml
Testosterone Sustanon 250 200mg/ml / 250mg/ml
Testosterone Supertest 450 450mg/ml
Nandrolone Decanoate (DECA) 200 / 250 / 300mg/ml
Trenbolone Acetate 100mg/ml
Trenbolone Enanthate(parabola) 200mg/ml
Drostanolone Propionate (Masteron) 100mg/ml
Boldenone Undecylenate (Equipoise) 200mg/ml / 300mg/ml
Methenolone Acetate (Primobolone) 100mg/ml
Anomass 400mg/ml
Ripex 225mg/ml
Tritren 180mg/ml
More More

 

Related Peptides:

 

Peptides List Specification
MGF 2mg
PEG MGF 2mg
CJC-1295 with DAC 2mg
CJC-1295 without DAC 2mg
PT-141 10mg
MT-1(Melanotan-1) 10mg
MT-2(Melanotan-2) 10mg
GHRP-2 5mg
GHRP-2 10mg
GHRP-6 5mg
GHRP-6 10mg
Ipamorelin 2mg
Hexarelin 2mg
Sermorelin 2mg
Oxytocin 1g/2mg
TB500 2mg
pentadecapeptide BPC 157 2mg
Triptorelin 2mg
Tesamorelin 2mg
Gonadorelin 2mg
Gonadorelin 10mg
DSIP 2mg
Selank 5mg
Epitalon 10mg
AOD-9604 2mg
ACE 031 1mg
GDF-8 1mg(-20ºC)
Thyrotropin TRH 1g
Follistatin 315 1mg(-20ºC)
Follistatin 344 1mg(-20ºC)
Deslorelin 20mg
Adipotide 2mg

 

Alarelin Acetate 79561-22-1
Angiotensin Acetate 58-49-1
Argpressin Acetate 113-79-1
Aviptadil Acetate 40077-57-4
Bivalirudin Trifluoroacetate 128270-60-0
Deslorelin Acetate 57773-65-6
Desmopressin Acetate 16679-58-6
Eledoisin Acetate 69-25-0
Eptifibatide Acetate 148031-34-9
Felypressin Acetate 56-59-7
GLP-1 (7-37) Acetate 106612-94-6
Taspoglutide 275371-94-3
Glucagon Hydrochloride 16941-32-5
Lixisenatide 320367-13-3
Gonadorelin Acetate 34973-08-5
Leuprorelin Acetate 53714-56-0
Lysipressin Acetate 50-57-7
Nafarelin Acetate 76932-56-4
Octreotide 79517-01-4
Ornipressin Acetate 3397-23-7
Secretin Acetate 108135-74-8
Somatostatin Acetate 38916-34-6
Splenopentin Acetate 105184-37-0
Terlipressin Acetate 14636-12-5
Teriparatide Acetate 52232-67-4
Triptorelin Acetate 57773-63-4
Vasopressin Acetate 9034-50-8
Bate-Amyloid(1-42)human 107761-42-2
Abarelix Acetate 183552-38-7
Endothelin-1 Acetate 117399-94-7
CRF (human, rat) Acetate 86784-80-7
CRF (ovine) Trifluoroacetate 79804-71-0
Dynorphin A (1-13) Acetate 72957-38-1
Enfuvirtide Acetate (T-20) 159519-65-0
Fertirelin Acetate 38234-21-8
GRF (human) Acetate 83930-13-6
Liraglutide 204656-20-2
Dalmarelin Acetate 61012-19-9
Nesiritide Acetate (BNP-32) 114471-18-0
Pramlintide Acetate 196078-30-5
Salmon Calcitonin Acetate 47931-85-1
tesamorelin 106612-94-6
Tetracosactide Acetate (ACTH 1-24) 16960-16-0
Thymosin α1 Acetate 14636-12-5
Thymosin β4 Acetate 77591-33-4
Atosiban Acetate 90779-69-4
Cetrorelix Acetate 130143-01-0
Exenatide Acetate 141732-76-5
Histrelin Acetate 76712-82-8
Taltirelin Acetate 103300-74-9
Vapreotide Acetate 116430-60-5
Gonaderelin 33515-09-2
Cecropin B 80451-05-4
Oxytocin Acetate 50-56-6
Sincalide 25126-32-3
Protirelin 24305-27-9
Ganirelix acetate 123246-29-7

 

SARMs:

 

Ostarine (MK-2866) CAS: 841205-47-8
Cardarine (GW-501516) CAS: 317318-70-0
Andarine (S4) CAS: 401900-40-1
Ligandrol (LGD-4033) CAS: 1165910-22-4
Ibutamoren (MK-677) CAS: 159752-10-0
RAD140 CAS: 118237-47-0
SR9009 CAS: 1379686-30-2
YK11 CAS: 431579-34-9
More

 

Sex Enhancers:

 

Avanafil CAS: 330784-47-9
Vardenafil CAS: 224785-91-5
CAS: 119356-77-3
Tadalafil CAS: 171596-29-5
Vardenafil Hydrochloride CAS: 431579-34-9
Hydrochloride CAS: 431579-34-9
Yohimbine Hydrochloride CAS: 65-19-0

 

APIs:

 

T3 CAS: 55-06-1
T4 CAS: 51-48-9
Ethyl Oleate(EO) CAS: 111-62-6
Benzyl Alcohol (BA) CAS: 100-51-6
Benzyl Benzoate (BB) CAS: 120-51-4
Grape Seed Oil (GSO) CAS: 85594-37-2
2,4-Dinitrophenol (DNP) CAS: 51-28-5
1,3-Dimethylpentylamine (DMAA) CAS: 13803-74-2
4-Acetamidophenol (Paracetamol) CAS:103-90-2
Tauroursodeoxycholic Acid (TUDCA) CAS: 14605-22-2
Dextromethorphan Hydrobromide (DXM) CAS: 6700-34-1

 129453-61-8 Pharmaceutical Raw Materials Anti Estrogen Steroids Fulvestrant Faslodex For Cutting Cycle 1

 

Package

 

We do understand that you will be worried about our packing methods before you tried or knew us, while we are making the real deal and we do know how customs works.

 

We have professional team for special disguised package, no word concern steroid will be whown on the parcels, the pass custom rate is more than 99%.

 

Before we could be able to offer some details of our package and shipping methods, and it is better to discuss by mail , skype or whatsapp.

 

 

Delivery

 

Our company owns a professional and efficient team for packing with our best discrete or stealth packages. Orders will be sent out within only one working day after payment.Package details and tracking number will be sent to you.Shipment by DHL, TNT, FedEx, HKEMS, UPS, ,EUB,ETK and so on.

 

It usually takes 4 to 7 days or 7 to 10 days by some other express courier; it will be 15 to 20 days by slow post.

 

Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.

 

We will stack on the parcels until you get them on hand so that you do not need to spare time on this.

 

 

 

Our commitment:

 

1. Quality assurance

With our years of experience, advanced technology and continuous research, our quality is to fully meet the needs of the market to meet the requirements of customers, many customers use our products, we believe that the product is very good. Whether it is a powder, or liquid, yes, we all know, our liquid better.

 

2. Safe transportation

Our mode of transport is taken according to each country's situation is different transportation, while our packaging, according to the latest customs situation, constantly updated, improved our packaging, we guarantee that you receive it within 3-5 to your product.

 

3. The product diversity

Our products are powders and liquids, yes, brothers, the effect of the liquid is very good, but many people do not use liquid, so you are very lucky, you buy our powder, we can tell you the method of making the liquid If you buy a liquid, we will tell you how to filter. We absolutely guarantee that you can very safely use our products

 

4. High quality service 

Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%, As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.

Contact Details
RAWSGEAR MANUFACTURER

Contact Person: Coco

Tel: +8618186204104

Send your inquiry directly to us (0 / 3000)