|Place of Origin:||China|
|Certification:||ISO 9001, USP,GMP|
|Minimum Order Quantity:||Negotiation|
|Packaging Details:||Well disguised package with new shipping 100% delivered|
|Delivery Time:||3~5 work days|
|Payment Terms:||Western Union, MoneyGram, T/T, Bitcoin|
|Supply Ability:||Mass in Stock|
|Product Name:||MGF||Full Name:||Mechano Growth Factor|
|Specification:||2mg/vial||Unit:||10vials Per Kit|
Muscles Growth Peptide MGF 2mg/Vial Mechano Growth Factor For Bodybuilders
1. Quick detail
Product name: MGF(2mg/vial,10vial/box)
Full name: Mechano Growth Factor
CAS number: 12020-86-9
Specification: 2mg/vial, 10vial/box
Appearance: White freeze-dried powder
Usage: Muscles Growth
Related product lists
|CJC-1295 with DAC||2mg|
|CJC-1295 without DAC||2mg|
|Pentadecapeptide BPC 157||2mg|
2. What is MGF ?
Mechano Growth Factor (MGF) also known as IGF-1Ec is a growth factor/repair factor that is derived from exercised or damaged muscle tissue. It's called MGF as IGF-IEa is a bit of a mouthful and harder to identify amongst the other IGF variants.
What makes MGF special is its' unique role in muscle growth. MGF has the ability to cause wasted tissue to grow and improve by activating muscle stem cells and increasing the upregulation of protein synthesis, this unique ability can rapidly improve recovery and speed up muscle growth. MGF can initiate muscle satellite (stem) cell activation in addition to its IGF-1 receptor domain which, in turn, increases protein synthesis turnover; therefore, if used correctly it can improve muscle mass over time.
The liver produces 2 kinds of MGF splice variants of IGF
1) IGF-1Ec: This is the first phase release igf splice variant and it appears to stimulate satellite cells into activation, This is the closest variant to synthetic MGF.
2) Liver type IGF-IEa: this is the secondary release of igf from the liver, and its far less anabolic.
It was first discovered in the muscle by Goldspink, et al. In human muscle, a 49-base insert changes the reading frame in mechano growth factor (MGF) as compared to IGF-1.
When mechanical overload is introduced to a muscle (as by weight training), the IGF-1 gene released and is differentially spliced during the bodies response. Initially, it it is spliced to produce predominantly IGF-1Ec (called the MGF splice variant of IGF-1). This early splicing stimulates satellite cells into activation. Which in turn allows the activation of extra undamaged nuclei to grow new muscle fiber and tissue. The appearance of MGF also initiates the upregulation of new protein synthesis. After this initial splicing of IGF-1 into MGF, production then switches towards producing a systemic release of IGF-1Ea from the liver, which also upregulates protein synthesis as well. The expression of IGF-1 splice variants, over the course of the healing and regrowth phase of muscle repair is thought to be the primary anabolic mechanism by which the body produces new muscle. MGF is available as an injectable peptide, and it has been anecdotally shown that injecting it will cause a response in the area resulting in localized muscle growth.
3. How to use MGF ?
When you train, what happens to your muscles is they break down, the cells are damaged, muscle tissue needs to be repaired and your body produces 2 forms of MGF splice variant. The first initial release of the above mentioned number 1 variant from the liver helps muscle cell recovery, if there is no MGF then muscle cells die.
As muscle is a post-mitotic tissue and as such cell replacement is not a means of tissue repair, if the cells are not repaired they die and your muscles get smaller and weaker. In muscle tissue, the pool of these stem cells is apparently replenished by the action of MGF, which is produced as a pulse following damage.
Now, with synthetic injections of MGF you can increase the pulse and so speed up recovery, and increase the muscle tissue cells by stimulating satellite cells into full maturity. In terms of dosages, 200mcg bi-laterally is the very best choice of dosing in muscles trained.
The only problem with MGF, and this is the reason I don't like it, is that it has such a short half life, just a few minutes, between 5-7, and it needs to be used immediately post workout as it wont work if muscle tissue hasn’t been damaged. That's why, for me personally, I think the best option is PEG MGF.
Nevertheless, MGF has a huge role to play, and is administered to those with muscle wasting diseases and for those who are elderly and have lost muscle mass for good reason, it is EXTREMELY anabolic.
4. MGF Effect
|a. Asingle intramuscular injection into muscle resulted in a 25% increase in mean muscle fibre cross section area within three weeks.|
|b. Using a similar protocol, liver-derived IGF-1 took four months to produce a 15% increase.|
|c. It would also appear that with regards to age, the young have a better ability to respond to MGF , and that the elderly experience a decreased response to MGF which results in a decreased ability to stimulate the growth of new muscle tissue.|
5. MGF usage
A typical protocol would be:
100-300mcg of MGF divided into 1-2 bilateral administrations in 2-5 different areas of the muscles approximately 5-7 days a week - intramuscular injections.
Example, if you want to administer 200mcg of MGF into the chest and biceps muscles 2 times a day and 3 different areas of the muscle then you would need to divided the dose as follows:
200mcg / 2 times per day = 100mcg per administration
100mcg per administration / 4 muscles (2 chest and 2 bicep muscles) = 25mcg per muscle
25mcg per muscle / 3 different locations on each muscle = 8.3mcg per injection
Theoreticall, the more locations used to administer the MGF into the muscle the more places for muscle growth.
|Appearance||White to off white powder||Consistent|
The biggest advantage from ou lab
1. High quality raws (>98% purity)
2. 100% safe package
3. USA base delivery
4. Special channel to EU
--- By Pharmlab
Tags: Mgf peptides , Mechano Growth Factor ,PEG MGF