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Ampicillin CAS: 7177-48-2 Pharmaceutical raw materials

Ampicillin CAS: 7177-48-2 Pharmaceutical raw materials

    • Ampicillin CAS: 7177-48-2 Pharmaceutical raw materials
    • Ampicillin CAS: 7177-48-2 Pharmaceutical raw materials
  • Ampicillin CAS: 7177-48-2 Pharmaceutical raw materials

    Product Details:

    Place of Origin: China
    Brand Name: Pharmlab
    Certification: ISO 9001, USP,GMP
    Model Number: CAS: 7177-48-2

    Payment & Shipping Terms:

    Minimum Order Quantity: 10g
    Price: negotiation
    Packaging Details: Well disguised pacakge ; USA based delivery
    Delivery Time: 3~5 work days
    Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
    Supply Ability: Mass in stock
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    Detailed Product Description
    Product Name: Ampicillin Product Catagory: Ampicillin Steroid Powder
    Product Secification: White Crystalline Powder Shipping Method: EMS,HKEMS,FEDEX,DHL,UPS,Aramex,ETC
    Shipping Policy: 100% Resend Policy Shipping Way: Special Safe Shipping To EU ; USA Based Delivery
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    Product Name: Ampicillin (Ampicillin)
    CAS: 7177-48-2
    Natural / Synthetic: Synthetic
    Source of extraction: Sanshui
    Level: Medical grade
    Appearance: white powder
    Packing: 25KG/ cardboard drum detachable
    Ingredients: This product is (2S,5R,6R)-3,3-dimethyl-6-[(R)-2-amino-2-phenylacetamido]-7-oxo-4-thia-1 - azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate. This is originally a trihydrate compound.
    Industry: Pharmaceutical raw materials
    Field: Intermediates
    Deferred product: Ampicillin sodium
    Use: Ampicillin sodium intermediate
    Dosage: by process


    Ampicillin, also known as ampicillin and ampicillin, is less effective than most penicillins for most Gram-positive bacteria. However, it has a strong effect on most Gram-negative bacteria, such as Escherichia coli, Proteus, Salmonella, Haemophilus, Brucella and Pasteurella, similar to or slightly stronger than chloramphenicol and tetracycline. However, the toxic effect is less than chloramphenicol or tetracycline. It is not effective against Staphylococcus aureus and Pseudomonas aeruginosa Ampicillin is widely used in human and animal lungs, urinary tract infections and certain infections caused by Gram-negative bacilli caused by sensitive bacteria, such as human meningitis, endocarditis, etc.; sputum, sputum pneumonia, bovine Pasteurellosis , pneumonia, mastitis, porcine contagious pleuropneumonia, chicken white mites, poultry typhoid and so on. Ampicillin is susceptible to decomposition by β-lactamase produced by bacteria, which reduces the therapeutic effect. It is often used in combination with the synthetic β-lactamase inhibitor-sulbactam to increase its synergistic effect. Its antibacterial activity has expanded its antibacterial spectrum. In addition, ampicillin and aminoglycoside antibiotics also have synergistic effects, which can enhance the efficacy.



    Use It can semi-synthetic broad-spectrum penicillin. This product is not resistant to enzymes, stable to acid and low in toxicity. It has inhibitory effects on Gram-negative bacteria and positive bacteria, and has a strong effect on E. coli, influenza bacillus, Salmonella, Shigella and some Proteus.
    Uses for the treatment of sensitive enterococci, dysentery bacilli, typhoid bacillus, Escherichia coli, Listeria, aerobacteria, influenza bacillus and Proteus mirabilis
    Production method First, the side chain carboxylic acid of D(-)-phenylglycine was used as a chlorinating agent PCI5. The acid chloride is formed and then subjected to a condensation reaction with 6-APA. Acetone and water were added to the reaction tank, and 6-APA was added thereto at a temperature of -5 to -10 ° C, followed by addition of phenylglycyl chloride. After 0.5 h of reaction, the pH was adjusted to 3.5 with 10% sodium hydroxide. The reaction was extracted with toluene. The aqueous layer was taken and the pH was adjusted to about 3.0 with 10% aqueous ammonia. Decolorize with activated carbon and filter. The filtrate was then adjusted with aqueous ammonia to give a pH of 4.8. The mixture was allowed to stand, then filtered, washed with acetone, and dried under vacuum at 40 ° C to obtain a product.


    Ampicillin CAS: 7177-48-2 Pharmaceutical raw materials 0


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    Ampicillin CAS: 7177-48-2 Pharmaceutical raw materials 1



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