|Place of Origin:||China|
|Certification:||ISO 9001, USP,GMP|
|Minimum Order Quantity:||10g|
|Packaging Details:||Well disguised package ; Foil bag 25kg/drum; 1kg/foil bag|
|Delivery Time:||3-5 work days|
|Payment Terms:||T/T, Western Union, MoneyGram|
|Product Name:||Oxytocin||Suitable For:||Adult|
|Shipping Method:||EMS,HKEMS,FEDEX,DHL,TNT,Aramex,ETC||Appearance:||White Lyophilized Powder|
98% Muscle Growth Polypeptide Hormones Oxytocin powder CAS 50-56-6
|Usage||Oxytocin is the principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland.|
|Synonyms||+CYS-TYR-ILE-GLN-ASN-+CYS-+PRO-LEU-GLY-NH2;CYS-TYR-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2;CYIQNCPLG-NH2;CYIQNCPLG-NH2 (DISULFIDE BRIDGE: 1-6);H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2;H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2,CYS1,6,CYCLIC;H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2 (DISULFIDE BRIDGE:1-6)A-HYPOPHAMINE|
Description of Oxytocin
Oxytocin is also called Pitocin, is a kind of uterine contraction medicine, can be extracted from animal posterior pituitary or chemical synthesis, chemical synthesis including on vasopressin, no booster effect, selective excitate uterine smooth muscle, strengthen its contracting, uterus is most sensitive to oxytocin (estrogen secretion increase) when parturient , immature uterus have no reactivity to this product, pregnancy early or middle uterine have low reactivity to oxytocin, late pregnancy is gradually increased, and before the antepartum, the reactivity is the highest. Small dose can strengthen the smooth muscle contraction rhythm at the bottom of the uterine, to reinforce the contraction force, contraction frequency, shrinkage properties similar to those in natural birth, and keep the polarity and symmetry, so the clinical used in hastening parturition, inducing abortion.
Large dose make uterine muscle tetanic contraction, clinical to oppression blood vessels between muscle fibers, to prevent and treatment of postpartum hemorrhage and postpartum subinvolution, and has the effect to promote lactation, the breast duct contraction, prompting milk from the breast, but cannot increase milk secretion, only can promote the milk. It is important to strictly master the dose and dripping speed for hastening parturition or inducing abortion, lest cause tetanic uterine contractions, killing fetal distress or uterine rupture. Every cephalopelvic disproportion , malposition or other abnormality, it is forbidden , abnormal uterine contraction, has a history of cesarean section and 3 or more times a multipara is forbidden .
Application of Oxytocin
In recent years, it is found that this product has good effect on pulmonary hemoptysis, and vagus nerve after resection or relaxation of gastrointestinal function after abdominal surgery. This product can absorb from the oral mucosa, and selectively acts on the smooth muscle of the uterus, make uterine contractions. Apply to hastening parturition and slow painful. Effect is the same as the static drops of oxytocin. For contracted pelvis, has a history of uterine surgery (including cesarean section), pain excessive hyperfunction, birth canal obstruction, severe placental abruption, maternal pregnancy poisoning are prohibited.
Common used with ergot preparations, treatment for postpartum hemorrhage; Inevitable abortion; Mainly used in late pregnancy induced labor and intrapartum uterine contractions fatigue caused by prolonged labor; Used for oxytocin sensitive test; Used for oxytocin irritability test; Assist in postpartum milk discharge; Haemoptysis. Postoperative gastrointestinal peristalsis slowly.
What does oxytocin do?
The answer depends on whether the individual is male or female.
In women, oxytocin is responsible for signal contraction in the uterus during labor. Hormones stimulate the uterine muscle contraction, so the labor begins. This also increases the production of prostaglandins, which makes the labor force gradually increased and increases the contraction.
Because of this effect, if women can not start naturally, sometimes the use of synthetic oxytocin to induce women to start work, or if women's labor force slows down, can give stronger women.
Once the baby is born, oxytocin promotes breastfeeding by moving the milk into the breast. When the baby sucks the mother's breast, the oxytocin secretion causes the milk to release, so the baby can feed. At the same time, oxytocin is released into the brain to stimulate the further production of oxytocin. Once the baby stops feeding, the hormone production stops until the next feeding.
For men, oxytocin is less important, but it does work in moving sperm. It also appears to affect testosterone production in the testes.
Recent oxytocin studies have found that it is an important chemical messenger that controls some human behavior and social interaction. It is oxytocin that triggers the connection between the mother and the baby, and may also play a role in recognition, sexual arousal, trust and anxiety. Some studies have shown that hormones may also affect addiction and stress.
Dosage and usage
1) Adult DoseInitial dose:
0.5 to 1 milliunits IV infusion per hour. At 30 to 60 minute intervals the dose should be gradually increased in increments of 1 to 2 milliunits until the desired contraction pattern has been established.
2) Usual Adult Dose for Postpartum Bleeding
10 to 40 units IV infusion in 1000 mL at a rate sufficient to control bleeding.
10 units IM after delivery of placenta.
After suction or sharp curettage for an incomplete, inevitable or elective abortion:
10 units in 500 mL IV infusion. Adjust rate to assist uterus in contraction.
After intra-amniotic injection for midtrimester elective abortion:
10 to 20 milliunits per minute IV infusion. The total dose should not exceed 30 units in a 12 hour period due to the risk of water intoxication.
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