|Place of Origin:||EMS,HKEMS,FEDEX,DHL,UPS,Aramex,ETC|
|Certification:||ISO 9001, USP,GMP|
|Model Number:||CAS 96-48-0|
|Minimum Order Quantity:||100ml|
|Packaging Details:||Well disguised package ; Plastic drum with safe shipping|
|Delivery Time:||3~5 work days|
|Payment Terms:||Western Union, MoneyGram, T/T, Bitcoin|
|Supply Ability:||Mass in stock|
|Product Name::||Gamma-Hydroxybutyrate||Alias::||GBL; GHB|
|Appearance::||Clear Colorless Oily Liquid||Whatsapp::||+8613027196769|
|Shipping Method::||EMS,HKEMS,FEDEX,DHL,UPS,Aramex,ETC||Shipping Policy::||100% Resend Policy If Parcel Seized|
Legit Sell Pharmaceutical GBL Gamma-Hydroxybutyrate CAS 96-48-0 GHB Improving Sleep
Product Name: gamma-Butyrolactone; GBL
Chemical Properties: Clear colorless oily liquid with a pleasant odor
Product Categories: Pharmaceutical Intermediates;Heterocycles;Miscellaneous Reagents;Halogenated Heterocycles ,Thiophenes ,Thiazolines/Thiazolidines
Specification : Magic GBL with Magic effect
Usage: Gamma-butyrolactone is one kind of important fine chemicalintermediate, simultaneously also is one kind of performance fine highboiling point solvent, ideal antioxidant, plasticizer,extracting agent, absorbent, dispersing agent, solid stain, Coagulation Reagent.
1. GBL Magic Cleaner is a cleaning liquid ,has unique clean strength .
2. GBL is used to produce the GHB with NaOH . GHB has been classified as a Class C drug .
3. people take gamma butyrolactone (GBL) for improving sleep, athletic performance and sexual performance and pleasure. They also take it for relieving depression and stress, promoting clear thinking, prolonging life, causing relaxation, and releasing growth hormone. GBL is also used to trim fat and as a body- or muscle-builder. Some people take it as a recreational drug.
GBL/GHB Chemical information for reference :
|Melting point||−45 °C|
|Boiling point||204-205 °C|
|density||1.12 g/mL at 25 °C|
|vapor density||3 (vs air)|
|vapor pressure||1.5 mm Hg ( 20 °C)|
|Refractive index||n20/D 1.436|
|Stability:||Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong acids, strong bases, strong reducing agents.|
|CAS DataBase Reference||96-48-0(CAS DataBase Reference)|
|NIST Chemistry Reference||«gamma»-Butyrolactone(96-48-0)|
|EPA Substance Registry||2(3H)-Furanone, dihydro-(96-48-0)|
GBL description :
GBL is a hygroscopic colorless liquid with a weak characteristic odor which is soluble in water. GBL is a common solvent and reagent in chemistry as well as being used as a flavouring, as a cleaning solvent, as a superglue remover, and as a solvent in some wet aluminium electrolytic capacitors. In humans it acts as a prodrug for GHB, and it is used as a recreational intoxicant with effects similar to alcohol. :)
GBL is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non-nucleophilic base, like lithium diisopropylamide, GBL can become an alpha-carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.
GBL is rapidly converted into GHB by paraoxonase (lactonase) enzymes, found in the blood. Animals which lack these enzymes exhibit no effect from GBL. GBL is more lipophilic (fat soluble) than GHB, and so is absorbed faster and has higher bioavailability. Because of these pharmacokinetic differences, GBL tends to be more potent and faster-acting than GHB, but has a shorter duration; whereas the related compound 1,4-butanediol (1,4-B) tends to be slightly less potent, slower to take effect but longer-acting than GHB.
Gamma-butyrolactone is a highly soluble, non-toxic, safe and easy to use high boiling point solvent, used in petroleum processing as butadiene, aromatic, advanced grease extractor; used in the chemical fiber industry Acrylonitrile fiber spinning solvent, wool, nylon, acrylonitrile and other fiber dyeing auxiliaries. In organic synthesis, GBL is also widely used, it is the synthesis of α-pyrrolidone, N-methyl pyrrolidone, vinyl pyrrolidone, acetyl-γ-butyrolactone, cyclopropylamine and other raw materials, synthetic insecticides, weeding Agents, drug brain rehabilitation, ciprofloxacin, vitamin B1, chlorophyll and other intermediates. Also used in the synthesis of chlorophenoxy butyric acid herbicides, plant growth regulators.
Gamma-butyrolactone process studies :
1. Maleic anhydride hydrogenation method The process is the development of the 1970s advanced technology, with a hydrogenation reaction, in any proportion of production of tetrahydrofuran and γ-butyrolactone, the usual ratio is tetrachlorofuran: γ-butyrolactone = 3-4: 1. Production enterprises more, but small scale, an average of 300t / a. The production capacity of the total domestic production capacity of 30%.
2. 1,4-butanediol dehydrogenation reactor for the tube, filled with flake copper catalyst (zinc oxide as the carrier). The reaction temperature is controlled at 230-240 ° C. The reaction product of crude γ-butyrolactone was distilled under reduced pressure to obtain a finished product in a yield of 77% or more.
The preparation method is based on 1,4-butanediol as raw material, the first preheating, and hydrogen in the presence of copper catalyst reaction, the temperature control in the 230 ~ 240 ℃, to obtain crude γ-butyrolactone, vacuum distillation product.
At present, maleic anhydride has been obtained by hydrogenation of succinic anhydride, and then further hydrogenation dehydration products.
The ramification of GBL:
|1. Can be hydrolyzed to produce γ-hydroxy butyric acid, can be used as a special plasticizer plastic, pharmaceutical intermediates;|
|2. Can be oxidized to produce succinic acid; reduced to 4-hydroxy butyraldehyde, and then reduced to 1,4-butanediol;|
|3. Can be condensed to produce α, α - dihydroxy ketone acetal;|
|4. Can react with CH3NH2 to form N-methyl-2-pyrrolidone;|
|5. Can generate tetrahydrofuran;|
|6. Can react with SO3 to form butyrolactone-α-sulfonic acid;|
7. Can react with NaCN to form 2-piperidone;
|8. Can react with CO to produce glutaric acid;|
|9. Can react with NaOH to produce 4,4 - oxo succinic acid;|
10. Can react with Na2S to form thiolated succinic acid;
With NA2SO3 reaction to generate sodium γ-sulfobutyrate.
Chemical analysis data of GBL :
|Purity (GC, wt%)||≥99.5|
|Purity (GC, wt%)||≤0.05|
|Purity (GC, wt%)||≤25|
|Purity (GC, wt%)||1.125~1.135|
|Refractive index (@20degree)||1.435~1.438|
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